MedKoo Cat#: 145924 | Name: Amidepin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Amidepin is a medication classified as a calcium channel blocker, primarily used to treat hypertension (high blood pressure) and angina (chest pain). It works by inhibiting the influx of calcium ions into smooth muscle cells and cardiac cells through voltage-gated calcium channels, resulting in vasodilation and reduced heart contractility. This mechanism helps to lower blood pressure and alleviate the workload on the heart. Additionally, amidepin can improve blood flow by relaxing the blood vessels, thus providing relief from conditions related to cardiovascular strain.

Chemical Structure

Amidepin
Amidepin
CAS#90405-00-8

Theoretical Analysis

MedKoo Cat#: 145924

Name: Amidepin

CAS#: 90405-00-8

Chemical Formula: C20H24N2O3S

Exact Mass: 372.1500

Molecular Weight: 372.48

Elemental Analysis: C, 64.49; H, 6.49; N, 7.52; O, 12.89; S, 8.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Amidepin;
IUPAC/Chemical Name
2-(diethylamino)-N-(5,5-dioxido-6,11-dihydrodibenzo[b,e]thiepin-11-yl)acetamide
InChi Key
FSQJFCZVACUULT-UHFFFAOYSA-N
InChi Code
1S/C20H24N2O3S/c1-3-22(4-2)13-19(23)21-20-16-10-6-5-9-15(16)14-26(24,25)18-12-8-7-11-17(18)20/h5-12,20H,3-4,13-14H2,1-2H3,(H,21,23)
SMILES Code
CCN(CC)CC(=O)NC1C2=CC=CC=C2CS(=O)(=O)C3=CC=CC=C13
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 372.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Stehlík P, Houbová H. Determination of amidepin in human plasma by reversed- phase high-performance liquid chromatography with fluorescence detection. J Chromatogr. 1991 Apr 19;565(1-2):477-81. doi: 10.1016/0378-4347(91)80413-7. PMID: 1874897. 2: Peterková M, Matousová O, Ryska M, Koruna I, Rejholec V. Fluorescencní reakce Amidepinu s N-bromsuccinimidem [Fluorescence reaction of Amidepine with N-bromosuccinimide]. Cesk Farm. 1988 May;37(4):159-61. Czech. PMID: 3396087. 3: Heinc P, Lukl J, Cíhalík C. Vliv amidepinu na vyvolatelnost komorové tachykardie programovanou stimulací komor [The effect of amidepine on induction of ventricular tachycardia using programmed ventricular stimulation]. Vnitr Lek. 1994 Aug;40(8):482-4. Czech. PMID: 7941431.