Synonym
Tartaramide; NSC-38709; NSC 38709; NSC38709;
IUPAC/Chemical Name
(2R,3R)-2,3-dihydroxysuccinamide
InChi Key
GRMNJXQBRPJVQV-JCYAYHJZSA-N
InChi Code
1S/C4H8N2O4/c5-3(9)1(7)2(8)4(6)10/h1-2,7-8H,(H2,5,9)(H2,6,10)/t1-,2-/m1/s1
SMILES Code
NC(=O)[C@H](O)[C@@H](O)C(N)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
148.12
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Konno H, Sasaki M, Sano H, Osawa K, Nosaka K, Yano S. The Hydrophobicity and Antifungal Potentiation of Burkholdine Analogues. Molecules. 2022 Feb 10;27(4):1191. doi: 10.3390/molecules27041191. PMID: 35208979; PMCID: PMC8877233.
2: Meng Y, Xiao Q, Bai JY, Xiao X, Zhang S, Zhu XY, Cheng GF, Yin DL. Resolution and chiral recognition of muscone as well as actions on neural system. J Asian Nat Prod Res. 2014 Dec;16(12):1166-70. doi: 10.1080/10286020.2014.996141. Epub 2015 Jan 6. PMID: 25559500.
3: Smith RJ, Capaldi RA, Muchmore D, Dahlquist F. Cross-linking of ubiquinone cytochrome c reductase (complex III) with periodate-cleavable bifunctional reagents. Biochemistry. 1978 Sep 5;17(18):3719-23. doi: 10.1021/bi00611a007. PMID: 212103.
4: Lee CC, Liu Y, Reineke TM. General structure-activity relationship for poly(glycoamidoamine)s: the effect of amine density on cytotoxicity and DNA delivery efficiency. Bioconjug Chem. 2008 Feb;19(2):428-40. doi: 10.1021/bc7001659. Epub 2008 Jan 16. PMID: 18197609.
5: Coggins JR, Lumsden J, Malcolm AD. A study of the quaternary structure of Escherichia coli RNA polymerase using bis(imido esters). Biochemistry. 1977 Mar 22;16(6):1111-6. doi: 10.1021/bi00625a013. PMID: 321015.
6: Oxelbark J, Sellén IB. Effects from hydrogen bonding and rigidity on selectivity in tartaric acid-based chiral selectors for enantioselective liquid chromatography. Chirality. 2003 Nov;15(9):787-93. doi: 10.1002/chir.10299. PMID: 14556216.
7: Ring D, Cole RD. Chemical cross-linking of H1 histone to the nucleosomal histones. J Biol Chem. 1979 Nov 25;254(22):11688-95. PMID: 500667.
8: van Heyningen S. Activity of covalently cross-linked cholera toxin with the adenylate cyclase of intact and lysed pigeon erythrocytes. Biochem J. 1977 Dec 15;168(3):457-63. doi: 10.1042/bj1680457. PMID: 606247; PMCID: PMC1183793.