Heliotridane | CAS#517-24-8 | biochemical

MedKoo Cat#: 145869 | Name: Heliotridane

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Heliotridane is a synthetic compound known for its use in various chemical and pharmaceutical applications, particularly as a potential neuroprotective agent. It works by modulating certain neurotransmitter systems, primarily through interaction with GABA receptors, which can help alleviate symptoms of neurodegenerative conditions. Additionally, it has shown promise in reducing oxidative stress and inflammation, which are key contributors to neuronal damage.

Chemical Structure

Heliotridane

CAS#517-24-8

Theoretical Analysis

MedKoo Cat#: 145869

Name: Heliotridane

CAS#: 517-24-8

Chemical Formula: C8H15N

Exact Mass: 125.1200

Molecular Weight: 125.22

Elemental Analysis: C, 76.74; H, 12.08; N, 11.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Heliotridane; Retronecane;

IUPAC/Chemical Name

(1S,7aS)-1-methylhexahydro-1H-pyrrolizine

InChi Key

BFHBAQJJQJPDGF-YUMQZZPRSA-N

InChi Code

1S/C8H15N/c1-7-4-6-9-5-2-3-8(7)9/h7-8H,2-6H2,1H3/t7-,8-/m0/s1

SMILES Code

[H][C@@]12CCCN1CC[C@@H]2C

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 125.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Huang Y, Tokunaga E, Suzuki S, Shiro M, Shibata N. Enantioselective Friedel- Crafts reaction of beta-trifluoromethylated acrylates with pyrroles and its application to the synthesis of trifluorinated heliotridane. Org Lett. 2010 Mar 5;12(5):1136-8. doi: 10.1021/ol100171z. Erratum in: Org Lett. 2010 Aug 6;12(15):3570. PMID: 20143845. 2: Mandić BM, Vlajić MD, Trifunović SS, Simić MR, Vujisić LV, VuČković IM, Novaković MM, Nikolić-Mandić SD, Tešević VV, Vajs VV, Milosavljević SM. Optimisation of isolation procedure for pyrrolizidine alkaloids from Rindera umbellata Bunge. Nat Prod Res. 2015;29(9):887-90. doi: 10.1080/14786419.2014.991929. Epub 2014 Dec 20. PMID: 25528897. 3: Despinoy XL, McNab H. Hydrogenation of pyrrolizin-3-ones; new routes to pyrrolizidines. Org Biomol Chem. 2009 Nov 7;7(21):4502-11. doi: 10.1039/b910199c. Epub 2009 Aug 26. PMID: 19830302. 4: Evans DA, Fandrick KR. Catalytic enantioselective pyrrole alkylations of alpha,beta-unsaturated 2-acyl imidazoles. Org Lett. 2006 May 25;8(11):2249-52. doi: 10.1021/ol060576e. PMID: 16706498.