MedKoo Cat#: 145856 | Name: Dipropargyl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dipropargyl is a chemical compound commonly used in industrial and cosmetic formulations as a preservative and antimicrobial agent. It works by disrupting the cellular processes of microorganisms, preventing their growth and proliferation. In cosmetic products, dipropargyl is valued for its ability to extend shelf life by preventing bacterial and fungal contamination. Its mechanism involves the inhibition of enzymatic activity within microbial cells, effectively halting their metabolic functions and ensuring product safety.

Chemical Structure

Dipropargyl
Dipropargyl
CAS#628-16-0

Theoretical Analysis

MedKoo Cat#: 145856

Name: Dipropargyl

CAS#: 628-16-0

Chemical Formula: C6H6

Exact Mass: 78.0500

Molecular Weight: 78.11

Elemental Analysis: C, 92.26; H, 7.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Dipropargyl; NSC-155174; NSC155174; NSC 155174; Birpopargyl;
IUPAC/Chemical Name
hexa-1,5-diyne
InChi Key
YFIBSNDOVCWPBL-UHFFFAOYSA-N
InChi Code
1S/C6H6/c1-3-5-6-4-2/h1-2H,5-6H2
SMILES Code
C#CCCC#C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 78.11 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Brain Res Bull. 1987 Jul;19(1):47-55. doi: 10.1016/0361-9230(87)90164-x. PMID: 3651840. 5: Dardouri R, Kandri Rodi Y, Saffon N, Essassi el M, Ng SW. 7-Chloro-1,5-dipropargyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione. Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 20;66(Pt 12):o3228. doi: 10.1107/S1600536810047008. PMID: 21589518; PMCID: PMC3011384. 6: Hazari PP, Schulz J, Vimont D, Chadha N, Allard M, Szlosek-Pinaud M, Fouquet E, Mishra AK. A new SiF-Dipropargyl glycerol scaffold as a versatile prosthetic group to design dimeric radioligands: synthesis of the [(18) F]BMPPSiF tracer to image serotonin receptors. ChemMedChem. 2014 Feb;9(2):337-49. doi: 10.1002/cmdc.201300458. Epub 2013 Dec 27. PMID: 24376058. 7: Gao M, Shang C, Li J, Han G, Tang J, Yuan Q, Huang F. Synthesis and Characterization of Block Copolymers of Poly(silylene diethynylbenzen) and Poly(silylene dipropargyl aryl ether). Polymers (Basel). 2021 May 7;13(9):1511. doi: 10.3390/polym13091511. PMID: 34067206; PMCID: PMC8125851. 8: Ye C, Huang R, Chiou MF, Wang B, Li D, Bao H. Synthesis of a new fluorophore: wavelength-tunable bisbenzo[f]isoindolylidenes. Chem Sci. 2023 Nov 2;14(45):13151-13158. doi: 10.1039/d3sc04445a. PMID: 38023512; PMCID: PMC10664550. 9: Kumar PS, Wurst K, Buchmeiser MR. Factors relevant for the regioselective cyclopolymerization of 1,6-heptadiynes, N,N-dipropargylamines, N,N-dipropargylammonium salts, and dipropargyl ethers by Ru(IV)-alkylidene-based metathesis initiators. J Am Chem Soc. 2009 Jan 14;131(1):387-95. doi: 10.1021/ja804563t. PMID: 19128182. 10: Ismail C, Nocentini A, Supuran CT, Winum JY, Gharbi R. 1,5-Benzodiazepines as a platform for the design of carbonic anhydrase inhibitors. Arch Pharm (Weinheim). 2022 Mar;355(3):e2100405. doi: 10.1002/ardp.202100405. Epub 2021 Dec 3. PMID: 34862650. 11: Cen J, Ye X, Liu X, Pan W, Zhang L, Zhang G, He N, Shen A, Hu J, Liu S. Fluorinated Copolypeptide-Stabilized Microbubbles with Maleimide-Decorated Surfaces as Long-Term Ultrasound Contrast Agents. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202209610. doi: 10.1002/anie.202209610. Epub 2022 Sep 1. PMID: 35976720. 12: Li KB, Wei XL, Zang Y, He XP, Chen GR, Li J, Chen K. Revisit of a dipropargyl rhodamine probe reveals its alternative ion sensitivity in both a solution and live cells. Analyst. 2013 Dec 7;138(23):7087-9. doi: 10.1039/c3an01379k. Epub 2013 Oct 3. PMID: 24091352. 13: Bonfield ER, Li CJ. Efficient ruthenium and copper cocatalzyed five- component coupling to form dipropargyl amines under mild conditions in water. Org Biomol Chem. 2007 Feb 7;5(3):435-7. doi: 10.1039/b613596j. Epub 2006 Dec 4. PMID: 17252122. 14: Kawka A, Nowak D, Koenig H, Pospieszny T. Exploring Triazole-Connected Steroid-Pyrimidine Hybrids: Synthesis, Spectroscopic Characterization, and Biological Assessment. ACS Omega. 2024 Aug 29;9(36):37995-38014. doi: 10.1021/acsomega.4c04800. PMID: 39281893; PMCID: PMC11391466. 15: Zi CT, Yang L, Xu FQ, Dong FW, Yang D, Li Y, Ding ZT, Zhou J, Jiang ZH, Hu JM. Synthesis and anticancer activity of dimeric podophyllotoxin derivatives. Drug Des Devel Ther. 2018 Oct 9;12:3393-3406. doi: 10.2147/DDDT.S167382. PMID: 30349193; PMCID: PMC6186772. 16: Al Ouahabi A, Charles L, Lutz JF. Synthesis of non-natural sequence-encoded polymers using phosphoramidite chemistry. J Am Chem Soc. 2015 Apr 29;137(16):5629-35. doi: 10.1021/jacs.5b02639. Epub 2015 Apr 20. PMID: 25851514. 17: Zheng Z, Yagafarov N, Xu Z, Ouali A, Takeda N, Liu Y, Unno M. BINOL and triazole-containing Janus rings and 29-8-29-membered tricyclic ladder-type hybridized siloxane: application in the fluorescence sensing of anions. Dalton Trans. 2023 Aug 1;52(30):10298-10304. doi: 10.1039/d3dt01320k. PMID: 37466385. 18: Chatterjee S, Ramakrishnan S. A novel photodegradable hyperbranched polymeric photoresist. Chem Commun (Camb). 2013 Dec 7;49(94):11041-3. doi: 10.1039/c3cc47048b. PMID: 24142040. 19: Ogunfowora LA, Singh I, Arellano N, Pattison TG, Magbitang T, Nguyen K, Ransom B, Lionti K, Nguyen S, Topura T, Delenia E, Sherwood M, Savoie BM, Wojtecki R. Reactive Vapor-Phase Inhibitors for Area-Selective Depositions at Tunable Critical Dimensions. ACS Appl Mater Interfaces. 2024 Jan 31;16(4):5268-5277. doi: 10.1021/acsami.3c14821. Epub 2024 Jan 11. PMID: 38206307. 20: Wu X, He J, Hu R, Tang BZ. Room-Temperature Metal-Free Multicomponent Polymerizations of Elemental Selenium toward Stable Alicyclic Poly(oxaselenolane)s with High Refractive Index. J Am Chem Soc. 2021 Sep 29;143(38):15723-15731. doi: 10.1021/jacs.1c06732. Epub 2021 Sep 14. PMID: 34520199.