Synonym
Teucvidin; NSC-258599; NSC258599; NSC 258599;
IUPAC/Chemical Name
(3R,5S,5a'R,7'R,8a'R)-5-(furan-3-yl)-7'-methyl-3',4,5,5',5a',7',8',8a'-octahydro-2H-spiro[furan-3,6'-naphtho[1,8-bc]furan]-2,2'(4'H)-dione
InChi Key
XJRMFKRYVTYFPN-BUQKYKDUSA-N
InChi Code
1S/C19H20O5/c1-10-7-14-16-12(17(20)23-14)3-2-4-13(16)19(10)8-15(24-18(19)21)11-5-6-22-9-11/h5-6,9-10,13-15H,2-4,7-8H2,1H3/t10-,13-,14-,15+,19-/m1/s1
SMILES Code
[H][C@]12C[C@@H](C)[C@]3(C[C@H](OC3=O)C4=COC=C4)[C@]5([H])CCCC(C(=O)O1)=C25
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
328.36
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Liu X, Lee CS. Total synthesis of (-)-teucvidin. Org Lett. 2012 Jun 1;14(11):2886-9. doi: 10.1021/ol301098s. Epub 2012 May 17. PMID: 22594711.
2: Zhan XQ, Wu Q, Wang MJ, Liu L, Cui WB, An FL, Qi FM, Fei DQ, Zhang ZX. A new diterpenoid from the leaves and twigs of Croton lachnocarpus Benth. Nat Prod Res. 2024 Apr;38(7):1184-1190. doi: 10.1080/14786419.2022.2135002. Epub 2022 Oct 19. PMID: 36260069.
3: Zhu YY, Li GY. [Studies on the diterpenoids on Teucrium quadrifarium Buch- Ham]. Yao Xue Xue Bao. 1993;28(9):679-83. Chinese. PMID: 8010014.
4: Sundaresan PR, Slavoff SA, Grundel E, White KD, Mazzola E, Koblenz D, Rader JI. Isolation and characterisation of selected germander diterpenoids from authenticated Teucrium chamaedrys and T. canadense by HPLC, HPLC-mS and NMR. Phytochem Anal. 2006 Jul-Aug;17(4):243-50. doi: 10.1002/pca.912. PMID: 16910040.