MedKoo Cat#: 128410 | Name: HIF-2α Translation Inhibitor 76
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HIF-2α translation inhibitor 76 is an inhibitor of hypoxia-inducible factor-2α (HIF-2α) translation.

Chemical Structure

HIF-2α Translation Inhibitor 76
HIF-2α Translation Inhibitor 76
CAS#882268-69-1

Theoretical Analysis

MedKoo Cat#: 128410

Name: HIF-2α Translation Inhibitor 76

CAS#: 882268-69-1

Chemical Formula: C9H9N3O4S2

Exact Mass: 287.0034

Molecular Weight: 287.31

Elemental Analysis: C, 37.62; H, 3.16; N, 14.63; O, 22.27; S, 22.32

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 650.00 2 Weeks
25mg USD 950.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
HIF-2α Translation Inhibitor 76; Hypoxia-Inducible Factor-2α Translation Inhibitor 76
IUPAC/Chemical Name
methyl (E)-3-(2-(cyano(methylsulfonyl)methylene)hydrazineyl)thiophene-2-carboxylate
InChi Key
OOGAPDPPVHJYGJ-KPKJPENVSA-N
InChi Code
InChI=1S/C9H9N3O4S2/c1-16-9(13)8-6(3-4-17-8)11-12-7(5-10)18(2,14)15/h3-4,11H,1-2H3/b12-7+
SMILES Code
CS(=O)(C(C#N)=NNC1=C(C(OC)=O)SC=C1)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 287.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Dai Z, Zhu MM, Peng Y, Machireddy N, Evans CE, Machado R, Zhang X, Zhao YY. Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in Pulmonary Arterial Hypertension with a HIF-2α Inhibitor. Am J Respir Crit Care Med. 2018 Dec 1;198(11):1423-1434. doi: 10.1164/rccm.201710-2079OC. PMID: 29924941; PMCID: PMC6290950.