MedKoo Cat#: 128388 | Name: IMC-14

Description:

WARNING: This product is for research use only, not for human or veterinary use.

IMC-14 is an Ultralong-acting Nondepolarizing Neuromuscular Blocker That Displays Short Onset Time and On-Demand Rapid Reversal by a Biocompatible Antagonist. IMC-14 displays extremely high blocking activity.

Chemical Structure

IMC-14
IMC-14
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128388

Name: IMC-14

CAS#: N/A

Chemical Formula: C50H56Cl4N8O2

Exact Mass: 0.0000

Molecular Weight: 942.85

Elemental Analysis: C, 63.70; H, 5.99; Cl, 15.04; N, 11.88; O, 3.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
IMC-14; IMC14; IMC 14; WY 70271; WY70271; WY-70271
IUPAC/Chemical Name
(12Z,72Z,112Z,172Z)-12,72,112,172-tetramethyl-11H,71H,111H,171H-4,14-dioxa-1,7,17(3,1),11(1,3)-tetraimidazol-3-iuma-3,5,13,15(1,4)-tetrabenzenacycloicosaphane-13,73,113,173-tetraium
InChi Key
AZWSEAKEXPXNQS-UHFFFAOYSA-N
InChi Code
InChI=1S/C50H56N8O2/c1-39-51-23-5-24-52-28-32-56(40(52)2)36-44-11-19-49(20-12-44)60-50-21-13-46(14-22-50)38-58-34-30-54(42(58)4)26-6-25-53-29-33-57(41(53)3)37-45-9-17-48(18-10-45)59-47-15-7-43(8-16-47)35-55(39)31-27-51/h7-22,27-34H,5-6,23-26,35-38H2,1-4H3/q+4
SMILES Code
CC1=[N+](C=CN1CCCN2C=C[N+]3=C2C)CC4=CC=C(OC5=CC=C(C[N+]6=C(C)N(CCCN(C=C7)C(C)=[N+]7CC8=CC=C(C=C8)OC9=CC=C(C3)C=C9)C=C6)C=C5)C=C4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 942.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Yang J, Wu Y, Liu YY, Yu SB, Feng K, Wang H, Zhou W, Ma D, Zhao G, Zhang J, Zhang DW, Li ZT. Discovery of an Ultralong-acting Nondepolarizing Neuromuscular Blocker That Displays Short Onset Time and On-Demand Rapid Reversal by a Biocompatible Antagonist. J Med Chem. 2025 Jan 24. doi: 10.1021/acs.jmedchem.4c03022. Epub ahead of print. PMID: 39854499.