MedKoo Cat#: 128360 | Name: DA-5

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DA-5 is a stable Dye for Bioimaging in the NIR-IIb Window.DA-5 exhibits superior properties, including excellent chemo- and photostability, resistance against solvatochromism-caused quenching, and antiaggregation in aqueous solution. With a large Stokes shift (241 nm) and high brightness (321 M−1 cm−1), DA-5 enables high-performance imaging of the lymphatic system, intestinal vessels, whole-body angiography, and cerebral and hindlimb microvasculature in NIR-IIb.

Chemical Structure

DA-5
DA-5
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128360

Name: DA-5

CAS#: N/A

Chemical Formula: C43H50BF4NO2S

Exact Mass: 731.3591

Molecular Weight: 731.74

Elemental Analysis: C, 70.58; H, 6.89; B, 1.48; F, 10.39; N, 1.91; O, 4.37; S, 4.38

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
DA-5; DA 5; DA5
IUPAC/Chemical Name
A name could not be generated for this structure.
InChi Key
HBFOXEBHDISQTQ-RULMAUPOSA-M
InChi Code
InChI=1S/C43H50NO2S.BF3.FH/c1-42(2)19-21-44-22-20-43(3,4)39-34-17-7-27(24-31(34)25-37(42)40(39)44)23-30-12-18-35-36(28-8-13-32(45-5)14-9-28)26-38(47-41(30)35)29-10-15-33(46-6)16-11-29;2-1(3)4;/h7-9,13-14,17,23-26,29,33H,10-12,15-16,18-22H2,1-6H3;;1H/q+1;;/p-1/b30-23+;;
SMILES Code
CC1(C2=CC3=C(C4=C2N(CC1)CCC4(C)C)C=CC(/C=C5C6=C(CC/5)C(C7=CC=C(C=C7)OC)=CC(C8CCC(CC8)OC)=[S+]6)=C3)C.FB(F)F.[F-]
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 731.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Wang T, Qin Y, Wang JY, Xu Y, Guo J, Zhu Y, Zhang H, Qin Y, Qi ZQ, Fu H, Liu YJ, Cui M, Zhou K. Less Is More: Donor Engineering of a Stable Molecular Dye for Bioimaging in the NIR-IIb Window. J Med Chem. 2025 Jan 19. doi: 10.1021/acs.jmedchem.4c02866. Epub ahead of print. PMID: 39829110.