MedKoo Cat#: 145689 | Name: Phytoalexine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phytoalexine is a stilbenoid. Phytoalexine is shown to prevent or reduce diseases such as cancer and coronary heart disease.

Chemical Structure

Phytoalexine
Phytoalexine
CAS#18377-50-9

Theoretical Analysis

MedKoo Cat#: 145689

Name: Phytoalexine

CAS#: 18377-50-9

Chemical Formula: C11H11NO3

Exact Mass: 205.0700

Molecular Weight: 205.21

Elemental Analysis: C, 64.38; H, 5.40; N, 6.83; O, 23.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Phytoalexine;
IUPAC/Chemical Name
methyl 1-methoxy-1H-indole-3-carboxylate
InChi Key
JAAYVMHPQAMBJS-UHFFFAOYSA-N
InChi Code
1S/C11H11NO3/c1-14-11(13)9-7-12(15-2)10-6-4-3-5-8(9)10/h3-7H,1-2H3
SMILES Code
CON1C=C(C(=O)OC)C2=CC=CC=C12
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 205.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: The MICAD Research Team. 5-[(E)-2-(4-[18F]Fluorophenyl)ethenyl]-1,3-benzenediol. 2006 Aug 22 [updated 2006 Sep 11]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641411. 2: Gocmez SS, Gacar N, Utkan T, Gacar G, Scarpace PJ, Tumer N. Protective effects of resveratrol on aging-induced cognitive impairment in rats. Neurobiol Learn Mem. 2016 May;131:131-6. doi: 10.1016/j.nlm.2016.03.022. Epub 2016 Mar 31. PMID: 27040098. 3: Aleynova-Shumakova OA, Dubrovina AS, Manyakhin AY, Karetin YA, Kiselev KV. VaCPK20 gene overexpression significantly increased resveratrol content and expression of stilbene synthase genes in cell cultures of Vitis amurensis Rupr. Appl Microbiol Biotechnol. 2014 Jun;98(12):5541-9. doi: 10.1007/s00253-014-5625-7. Epub 2014 Mar 4. PMID: 24584516. 4: Atanacković M, Posa M, Heinle H, Gojković-Bukarica L, Cvejić J. Solubilization of resveratrol in micellar solutions of different bile acids. Colloids Surf B Biointerfaces. 2009 Aug 1;72(1):148-54. doi: 10.1016/j.colsurfb.2009.03.029. Epub 2009 Apr 5. PMID: 19411167. 5: Kimura Y, Okuda H. Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma-bearing mice. J Nutr. 2001 Jun;131(6):1844-9. doi: 10.1093/jn/131.6.1844. PMID: 11385077. 6: Casabuono AC, Pomilio AB. Alkaloids from endophyte-infected Festuca argentina. J Ethnopharmacol. 1997 Jun;57(1):1-9. doi: 10.1016/s0378-8741(97)00031-7. PMID: 9234159. 7: Schneider Y, Vincent F, Duranton B, Badolo L, Gossé F, Bergmann C, Seiler N, Raul F. Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells. Cancer Lett. 2000 Sep 29;158(1):85-91. doi: 10.1016/s0304-3835(00)00511-5. PMID: 10940513. 8: Fukai T, Kaitou K, Terada S. Antimicrobial activity of 2-arylbenzofurans from Morus species against methicillin-resistant Staphylococcus aureus. Fitoterapia. 2005 Dec;76(7-8):708-11. doi: 10.1016/j.fitote.2005.06.012. Epub 2005 Oct 19. PMID: 16236463. 9: Galtieri A, Tellone E, Ficarra S, Russo A, Bellocco E, Barreca D, Scatena R, Laganà G, Leuzzi U, Giardina B. Resveratrol treatment induces redox stress in red blood cells: a possible role of caspase 3 in metabolism and anion transport. Biol Chem. 2010 Sep;391(9):1057-65. doi: 10.1515/BC.2010.100. PMID: 20536388. 10: Ouassou M, Mukhaimar M, El Amrani A, Kroymann J, Chauveau O. Biosynthèse des glucosinolates indoliques et rôle écologique de leurs modifications secondaires [Biosynthesis of indole glucosinolates and ecological role of secondary modification pathways]. C R Biol. 2019 Mar-May;342(3-4):58-80. French. doi: 10.1016/j.crvi.2019.03.005. Epub 2019 May 11. PMID: 31088733. 11: Carle R. Phytoalexine und ihre Bedeutung für die Resistenz höherer Pflanzen gegenüber Schadorganismen [Phytoalexins and their significance for the resistance of higher plants to harmful organisms]. Pharm Unserer Zeit. 1992 May;21(3):99-104. German. doi: 10.1002/pauz.19920210307. PMID: 1438473. 12: Müller KO. Die Phytoalexine, in Sicht einer allgemeinen Immunbiologie [Phytoalexins from the viewpoint of general immunobiology]. Zentralbl Bakteriol Parasitenkd Infektionskr Hyg. 1969 May 24;123(3):259-65. German. PMID: 5396067.