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MedKoo Cat#: 128347 | Name: Ciwujianoside B

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ciwujianoside B is a triterpenoid saponin that has been found in A. senticosus and has diverse biological activities.

Chemical Structure

Ciwujianoside B
Ciwujianoside B
CAS#114902-16-8

Theoretical Analysis

MedKoo Cat#: 128347

Name: Ciwujianoside B

CAS#: 114902-16-8

Chemical Formula: C58H92O25

Exact Mass: 1188.5928

Molecular Weight: 1189.35

Elemental Analysis: C, 58.57; H, 7.80; O, 33.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ciwujianoside B; Ciwujianoside-B; CiwujianosideB
IUPAC/Chemical Name
(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-(((2S,3R,4S,5S)-4,5-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6a,6b,9,9,12a-pentamethyl-2-methylene-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate
InChi Key
UPROOJBJZLZCGS-CHTHVDMYSA-N
InChi Code
InChI=1S/C58H92O25/c1-23-11-16-58(53(73)83-51-44(71)40(67)37(64)30(79-51)22-75-48-45(72)41(68)46(29(20-59)78-48)81-49-42(69)38(65)34(61)24(2)76-49)18-17-56(7)26(27(58)19-23)9-10-32-55(6)14-13-33(54(4,5)31(55)12-15-57(32,56)8)80-52-47(36(63)28(60)21-74-52)82-50-43(70)39(66)35(62)25(3)77-50/h9,24-25,27-52,59-72H,1,10-22H2,2-8H3/t24-,25-,27-,28-,29+,30+,31-,32+,33-,34-,35-,36-,37+,38+,39+,40-,41+,42+,43+,44+,45+,46+,47+,48+,49-,50-,51-,52-,55-,56+,57+,58-/m0/s1
SMILES Code
OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O)O)O)O[C@H]1OC[C@H]([C@H]([C@@H]([C@H]3O)O)O)O[C@H]3OC([C@]45[C@](CC(CC5)=C)([H])C6=CC[C@@]([C@@]7([C@@](C(C)([C@H](CC7)O[C@H]8[C@@H]([C@H]([C@H](CO8)O)O)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)C)([H])CC%10)C)([H])[C@]%10(C)[C@@]6(CC4)C)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,189.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Dong WR, Gao X, Li CX, Song Y, Chai JH, Liang J. Detection and Characterization of the Metabolites of Ciwujianoside B in Rats Based on UPLC- Fusion Lumos Orbitrap Mass Spectrometry. J Anal Methods Chem. 2024 May 22;2024:3187511. doi: 10.1155/2024/3187511. PMID: 38813478; PMCID: PMC11136543. 2: Li YR, Cao W, Guo J, Miao S, Ding GR, Li KC, Wang J, Guo GZ. Comparative investigations on the protective effects of rhodioside, ciwujianoside-B and astragaloside IV on radiation injuries of the hematopoietic system in mice. Phytother Res. 2011 May;25(5):644-53. doi: 10.1002/ptr.3313. Epub 2010 Oct 28. PMID: 21031634. 3: Yamauchi Y, Ge YW, Yoshimatsu K, Komastu K, Kuboyama T, Yang X, Tohda C. Memory Enhancement by Oral Administration of Extract of Eleutherococcus senticosus Leaves and Active Compounds Transferred in the Brain. Nutrients. 2019 May 22;11(5):1142. doi: 10.3390/nu11051142. PMID: 31121888; PMCID: PMC6567285. 4: Liu Y, Wang Z, Wang C, Si H, Yu H, Li L, Fu S, Tan L, Li P, Liu J, Zhao Y. Comprehensive phytochemical analysis and sedative-hypnotic activity of two Acanthopanax species leaves. Food Funct. 2021 Mar 15;12(5):2292-2311. doi: 10.1039/d0fo02814b. PMID: 33605281. 5: Kuang F, Xiang T. Molecular mechanism of Acanthopanax senticosus in the treatment of Alzheimer's disease based on network pharmacology and molecular docking. Mol Divers. 2023 Dec;27(6):2849-2865. doi: 10.1007/s11030-022-10586-3. Epub 2022 Dec 28. PMID: 36576665. 6: Kwon RH, Na H, Kim JH, Kim SA, Kim SY, Jung HA, Lee SH, Wee CD, Lee KS, Kim HW. Comprehensive profiling of phenolic compounds and triterpenoid saponins from Acanthopanax senticosus and their antioxidant, α-glucosidase inhibitory activities. Sci Rep. 2024 Nov 1;14(1):26330. doi: 10.1038/s41598-024-77574-5. PMID: 39487169; PMCID: PMC11530669. 7: Ge YW, Zhu S, Yoshimatsu K, Komatsu K. MS/MS similarity networking accelerated target profiling of triterpene saponins in Eleutherococcus senticosus leaves. Food Chem. 2017 Jul 15;227:444-452. doi: 10.1016/j.foodchem.2017.01.119. Epub 2017 Jan 26. PMID: 28274455.

View History

CJ-1383

CJ-1383