LNS-8801 is a synthetic pharmacologic agonist of GPER currently in early phase clinical trials and promotes apoptosis in human AML cells. LNS8801 induces AML cell death primarily through a caspase-dependent apoptosis pathway.
MedKoo Cat#: 145673
Name: LNS-8801
CAS#: 925419-53-0
Chemical Formula: C21H18BrNO3
Exact Mass: 411.0500
Molecular Weight: 412.28
Elemental Analysis: C, 61.18; H, 4.40; Br, 19.38; N, 3.40; O, 11.64
The following data is based on the product molecular weight 412.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
