MedKoo Cat#: 128314 | Name: JF0064

Description:

WARNING: This product is for research use only, not for human or veterinary use.

JF0064 is an AKR1B10 inhibitor.

Chemical Structure

JF0064
JF0064
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128314

Name: JF0064

CAS#: N/A

Chemical Formula: C12H2F8O2

Exact Mass: 329.9927

Molecular Weight: 330.13

Elemental Analysis: C, 43.66; H, 0.61; F, 46.04; O, 9.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
JF0064; JF 0064; JF-0064
IUPAC/Chemical Name
2,2',3,3',5,5',6,6'-octafluoro-[1,1'-biphenyl]-4,4'-diol
InChi Key
MOFZHBRFFAIMKM-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H2F8O2/c13-3-1(4(14)8(18)11(21)7(3)17)2-5(15)9(19)12(22)10(20)6(2)16/h21-22H
SMILES Code
FC1=C(F)C(O)=C(F)C(F)=C1C2=C(F)C(F)=C(O)C(F)=C2F
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 330.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Cousido-Siah A, Ruiz FX, Mitschler A, Porté S, de Lera ÁR, Martín MJ, Manzanaro S, de la Fuente JA, Terwesten F, Betz M, Klebe G, Farrés J, Parés X, Podjarny A. Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design. Acta Crystallogr D Biol Crystallogr. 2014 Mar;70(Pt 3):889-903. doi: 10.1107/S1399004713033452. Epub 2014 Feb 27. PMID: 24598757.