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MedKoo Cat#: 128309 | Name: TG8-69

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TG8-69 is an EP2 antagonist.

Chemical Structure

TG8-69
TG8-69
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128309

Name: TG8-69

CAS#: N/A

Chemical Formula: C19H18N6O

Exact Mass: 346.1542

Molecular Weight: 346.39

Elemental Analysis: C, 65.88; H, 5.24; N, 24.26; O, 4.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
TG8-69; TG8 69; TG869
IUPAC/Chemical Name
N-(2-(2-methyl-1H-indol-3-yl)ethyl)-4-(1H-tetrazol-5-yl)benzamide
InChi Key
MDBGNCCIBYXJAS-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H18N6O/c1-12-15(16-4-2-3-5-17(16)21-12)10-11-20-19(26)14-8-6-13(7-9-14)18-22-24-25-23-18/h2-9,21H,10-11H2,1H3,(H,20,26)(H,22,23,24,25)
SMILES Code
CC1=C(CCNC(C2=CC=C(C3=NN=NN3)C=C2)=O)C4=C(N1)C=CC=C4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 346.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Amaradhi R, Mohammed S, Banik A, Franklin R, Dingledine R, Ganesh T. Second- Generation Prostaglandin Receptor EP2 Antagonist, TG8-260, with High Potency, Selectivity, Oral Bioavailability, and Anti-Inflammatory Properties. ACS Pharmacol Transl Sci. 2022 Jan 25;5(2):118-133. doi: 10.1021/acsptsci.1c00255. PMID: 35187419; PMCID: PMC8844972. 2: Ganesh T, Banik A, Dingledine R, Wang W, Amaradhi R. Peripherally Restricted, Highly Potent, Selective, Aqueous-Soluble EP2 Antagonist with Anti-Inflammatory Properties. Mol Pharm. 2018 Dec 3;15(12):5809-5817. doi: 10.1021/acs.molpharmaceut.8b00764. Epub 2018 Nov 15. PMID: 30398879; PMCID: PMC6633905.

View History

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