MedKoo Cat#: 128304 | Name: (Z)-Semaxanib
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(Z)-Semaxanib (compound (z)-1) is a potent tyrosine kinase inhibitor.

Chemical Structure

(Z)-Semaxanib
(Z)-Semaxanib
CAS#194413-58-6

Theoretical Analysis

MedKoo Cat#: 128304

Name: (Z)-Semaxanib

CAS#: 194413-58-6

Chemical Formula: C15H14N2O

Exact Mass: 238.1106

Molecular Weight: 238.29

Elemental Analysis: C, 75.61; H, 5.92; N, 11.76; O, 6.71

Price and Availability

Size Price Availability Quantity
100mg USD 450.00 2 Weeks
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Related CAS #
No Data
Synonym
(Z)-Semaxanib; (Z)-SU5416; compound (z)-1
IUPAC/Chemical Name
(Z)-3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)indolin-2-one
InChi Key
WUWDLXZGHZSWQZ-WQLSENKSSA-N
InChi Code
InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)/b12-8-
SMILES Code
O=C(NC1=C/2C=CC=C1)C2=C/C3=C(C)C=C(C)N3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 238.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Ngai MH, So CL, Sullivan MB, Ho HK, Chai CL. Photoinduced Isomerization and Hepatoxicities of Semaxanib, Sunitinib and Related 3-Substituted Indolin-2-ones. ChemMedChem. 2016 Jan 5;11(1):72-80. doi: 10.1002/cmdc.201500475. Epub 2015 Nov 23. PMID: 26593399.