MedKoo Cat#: 128299 | Name: Tephrosin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tephrosin is a natural rotenoid which has potent antitumor activities.

Chemical Structure

Tephrosin
Tephrosin
CAS#76-80-2

Theoretical Analysis

MedKoo Cat#: 128299

Name: Tephrosin

CAS#: 76-80-2

Chemical Formula: C23H22O7

Exact Mass: 410.1366

Molecular Weight: 410.42

Elemental Analysis: C, 67.31; H, 5.40; O, 27.29

Price and Availability

Size Price Availability Quantity
1mg USD 650.00 2 Weeks
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Related CAS #
No Data
Synonym
Tephrosin; Deguelinol I; Hydroxydeguelin; (-)-Tephrosin;
IUPAC/Chemical Name
(7aR,13aR)-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-pyrano[2,3-c:6,5-f']dichromen-7(7aH)-one
InChi Key
AQBZCCQCDWNNJQ-AUSIDOKSSA-N
InChi Code
InChI=1S/C23H22O7/c1-22(2)8-7-12-15(30-22)6-5-13-20(12)29-19-11-28-16-10-18(27-4)17(26-3)9-14(16)23(19,25)21(13)24/h5-10,19,25H,11H2,1-4H3/t19-,23-/m1/s1
SMILES Code
O=C1[C@]2(O)[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC=C14
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 410.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Choi S, Choi Y, Dat NT, Hwangbo C, Lee JJ, Lee JH. Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells. Cancer Lett. 2010 Jul 1;293(1):23-30. doi: 10.1016/j.canlet.2009.12.012. Epub 2010 Jan 6. PMID: 20056314.