MedKoo Cat#: 128298 | Name: 2-NP
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

2-NP is a selective enhancer of STAT1 transcription. 2-NP can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells.

Chemical Structure

2-NP
2-NP
CAS#65182-56-1

Theoretical Analysis

MedKoo Cat#: 128298

Name: 2-NP

CAS#: 65182-56-1

Chemical Formula: C14H10N2O

Exact Mass: 222.0793

Molecular Weight: 222.25

Elemental Analysis: C, 75.66; H, 4.54; N, 12.60; O, 7.20

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
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Related CAS #
No Data
Synonym
2-NP; 2 NP; 2NP
IUPAC/Chemical Name
2-(1,8-naphthyridin-2-yl)phenol
InChi Key
AYKMXKNVEUMLFQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H10N2O/c17-13-6-2-1-5-11(13)12-8-7-10-4-3-9-15-14(10)16-12/h1-9,17H
SMILES Code
OC1=CC=CC=C1C2=NC3=NC=CC=C3C=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 222.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Lynch RA, Etchin J, Battle TE, Frank DA. A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells. Cancer Res. 2007 Feb 1;67(3):1254-61. doi: 10.1158/0008-5472.CAN-06-2439. PMID: 17283162.