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MedKoo Cat#: 556782 | Name: MFI8
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MFI8 is a Mitochondrial Fusion Inhibitor

Chemical Structure

MFI8
MFI8
CAS#694488-83-0

Theoretical Analysis

MedKoo Cat#: 556782

Name: MFI8

CAS#: 694488-83-0

Chemical Formula: C16H18ClNO

Exact Mass: 275.1077

Molecular Weight: 275.78

Elemental Analysis: C, 69.69; H, 6.58; Cl, 12.85; N, 5.08; O, 5.80

Price and Availability

Size Price Availability Quantity
50mg USD 250.00 2 Weeks
100mg USD 450.00 2 Weeks
1g USD 2,450.00 2 Weeks
2mg USD 3,850.00 2 Weeks
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Related CAS #
No Data
Synonym
MFI8; MFI-8; MFI 8;
IUPAC/Chemical Name
4-chloro-2-(1-((2,3-dimethylphenyl)amino)ethyl)phenol
InChi Key
DYILWFVSLLZIIR-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H18ClNO/c1-10-5-4-6-15(11(10)2)18-12(3)14-9-13(17)7-8-16(14)19/h4-9,12,18-19H,1-3H3
SMILES Code
ClC1=CC=C(C(C(C)NC2=CC=CC(C)=C2C)=C1)O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Patients undergoing radiotherapy for head and neck cancer often experience a decline in their quality of life due to the co-irradiation of salivary glands. Radiation-induced cellular senescence is a key factor contributing to salivary gland dysfunction. Interestingly, mitochondrial dysfunction and cellular senescence have been reported to be strongly interconnected and thus implicated in several aging-related diseases.

Preparing Stock Solutions

The following data is based on the product molecular weight 275.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Cinat D, Souza AL, Soto-Gamez A, Jellema-de Bruin AL, Coppes RP, Barazzuol L. Mitophagy induction improves salivary gland stem/progenitor cell function by reducing senescence after irradiation. Radiother Oncol. 2024 Jan;190:110028. doi: 10.1016/j.radonc.2023.110028. Epub 2023 Nov 24. PMID: 38007043.