BBC0403 is a selective BRD2 inhibitor. BBC0403 inhibits the progression of osteoarthritis pathogenesis in osteoarthritis-induced C57BL/6 male mice. TR-FRET and binding kinetics assays revealed that BBC0403 exhibited higher binding specificity for BRD2 compared to BRD3 and BRD4.
MedKoo Cat#: 556781
Name: BBC0403
CAS#: 2644662-83-7
Chemical Formula: C21H22N2O5
Exact Mass: 382.1529
Molecular Weight: 382.42
Elemental Analysis: C, 65.96; H, 5.80; N, 7.33; O, 20.92
The following data is based on the product molecular weight 382.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
