MedKoo Cat#: 128262 | Name: CP681301
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP681301 is a highly specific, brain-permeable inhibitor of Cdk5.

Chemical Structure

CP681301
CP681301
CAS#865317-32-4

Theoretical Analysis

MedKoo Cat#: 128262

Name: CP681301

CAS#: 865317-32-4

Chemical Formula: C17H22N4O

Exact Mass: 298.1794

Molecular Weight: 298.39

Elemental Analysis: C, 68.43; H, 7.43; N, 18.78; O, 5.36

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
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Related CAS #
No Data
Synonym
CP681301; CP 681301; CP-681301
IUPAC/Chemical Name
N-(5-cyclobutyl-1H-pyrazol-3-yl)-2-(4-(dimethylamino)phenyl)acetamide
InChi Key
PGTNTDKBRSQDNM-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H22N4O/c1-21(2)14-8-6-12(7-9-14)10-17(22)18-16-11-15(19-20-16)13-4-3-5-13/h6-9,11,13H,3-5,10H2,1-2H3,(H2,18,19,20,22)
SMILES Code
O=C(NC1=NNC(C2CCC2)=C1)CC3=CC=C(N(C)C)C=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 298.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Mukherjee S, Tucker-Burden C, Kaissi E, Newsam A, Duggireddy H, Chau M, Zhang C, Diwedi B, Rupji M, Seby S, Kowalski J, Kong J, Read R, Brat DJ. CDK5 Inhibition Resolves PKA/cAMP-Independent Activation of CREB1 Signaling in Glioma Stem Cells. Cell Rep. 2018 May 8;23(6):1651-1664. doi: 10.1016/j.celrep.2018.04.016. PMID: 29742423; PMCID: PMC5987254.