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MedKoo Cat#: 128261 | Name: Phenol Red
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phenol red (Phenolsulfonephthalein) is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .

Chemical Structure

Phenol Red
Phenol Red
CAS#143-74-8

Theoretical Analysis

MedKoo Cat#: 128261

Name: Phenol Red

CAS#: 143-74-8

Chemical Formula: C19H14O5S

Exact Mass: 354.0562

Molecular Weight: 354.38

Elemental Analysis: C, 64.40; H, 3.98; O, 22.57; S, 9.05

Price and Availability

Size Price Availability Quantity
1g USD 450.00 2 Weeks
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Related CAS #
No Data
Synonym
Phenol Red; Phenolsulfonephthalein
IUPAC/Chemical Name
3,3-bis(4-hydroxyphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide
InChi Key
BELBBZDIHDAJOR-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H
SMILES Code
O=S1(OC(C2=CC=C(O)C=C2)(C3=CC=C(O)C=C3)C4=CC=CC=C41)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 354.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sundarakrishnan A, Herrero Acero E, Coburn J, Chwalek K, Partlow B, Kaplan DL. Phenol red-silk tyrosine cross-linked hydrogels. Acta Biomater. 2016 Sep 15;42:102-113. doi: 10.1016/j.actbio.2016.06.020. Epub 2016 Jun 23. PMID: 27345138. 2: Mousavi SM, Meraji SH, Sanati AM, Ramavandi B. Phenol red dye removal from wastewater using TiO2-FSM-16 and Ni-FSM-16 photocatalysts. Heliyon. 2023 Mar 11;9(3):e14488. doi: 10.1016/j.heliyon.2023.e14488. PMID: 36925530; PMCID: PMC10011056. 3: Sun C, Guo N, Ye L, Miao L, Cao M, Yan M, Ding J. Quantitative detection of phenol red by surface enhanced Raman spectroscopy based on improved GA-BP. Spectrochim Acta A Mol Biomol Spectrosc. 2023 Aug 5;296:122663. doi: 10.1016/j.saa.2023.122663. Epub 2023 Mar 24. PMID: 37001264. 4: Kuncharoenwirat N, Chatuphonprasert W, Jarukamjorn K. Differential Impacts of Phenol Red on Benzo[a]pyrene and Dexamethasone-Modified Cytochrome P450s in Human Cancer Cells. Pak J Biol Sci. 2021 Jan;24(7):790-800. doi: 10.3923/pjbs.2021.790.800. PMID: 34486298. 5: Hao Y, Jin T, Zhu L, Zhao M, Wang S, Li Z, Tian L, Jie Y. Validation of the phenol red thread test in a Chinese population. BMC Ophthalmol. 2023 Dec 7;23(1):498. doi: 10.1186/s12886-023-03250-3. PMID: 38062441; PMCID: PMC10701964. 6: Vera M, Barahona MJ, Nova-Lamperti E, Nualart F, Ferrada L. The phenol red compound: A potential artifact in pharmacological induction of ferroptosis. Free Radic Biol Med. 2024 Sep;222:397-402. doi: 10.1016/j.freeradbiomed.2024.06.023. Epub 2024 Jun 27. PMID: 38944214. 7: Welshons WV, Wolf MF, Murphy CS, Jordan VC. Estrogenic activity of phenol red. Mol Cell Endocrinol. 1988 Jun;57(3):169-78. doi: 10.1016/0303-7207(88)90072-x. PMID: 3402660. 8: Liu Z, An T, Yuan R, Tian M, Yuan L, Zhang T, Cheng G. Comparision of the phenol red, gravimetric, and synthesized mPEG-PR methods for correcting water flux using the single-pass intestinal perfusion method. Eur J Pharm Sci. 2022 Sep 1;176:106255. doi: 10.1016/j.ejps.2022.106255. Epub 2022 Jul 5. PMID: 35798231. 9: Huijuan Y, Xiaohu D, Ze L, Wei C, Jian Z, Lei M, Shaohui S, Weidong L, Guoyang L. Role of phenol red in the stabilization of the Sabin type 2 inactivated polio vaccine at various pH values. J Med Virol. 2019 Jan;91(1):22-30. doi: 10.1002/jmv.25289. Epub 2018 Oct 9. PMID: 30133803. 10: Amran EN, Sudik S, Omar AF, Mail MH, Seeni A. Potential colorimetric detection of cancer cells using Phenol Red. Photodiagnosis Photodyn Ther. 2019 Sep;27:380-384. doi: 10.1016/j.pdpdt.2019.07.006. Epub 2019 Jul 10. PMID: 31301437.