OAHP is a highly selective probe for the detection of Cu2+. Hydrazide moiety of OAHP quenches probe fluorescence; however, upon its reaction with Cu, oxidative cleavage of the hydrazide moiety and intramolecular cyclization occurs, forming oxadiazole derivative with strong fluorescent properties. In this context, OAHP displayed significant fluorescence enhancement with increasing levels of Cu2+. OAHP could detect Cu2+ selectively with a detection limit of 18 nM (1.1 ppb). It showed exceptional selective performance and exquisite sensitivity. The method was applied successfully for monitoring Cu2+ in tap water samples with good accuracy (found% of 95.8-101.5%) and precisions (RSD<10%). OAHP was successfully applied for imaging Cu2+ in living cells, and this result indicates the potential of OAHP for selective detection of Cu2+ in complicated matrices.
MedKoo Cat#: 556379
Name: OAHP Probe
CAS#: N/A
Chemical Formula: C23H16ClN3O2
Exact Mass: 0.0000
Molecular Weight: 401.85
Elemental Analysis: C, 68.75; H, 4.01; Cl, 8.82; N, 10.46; O, 7.96
The following data is based on the product molecular weight 401.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
