Synonym
CBS-1118; CBS1118; CBS 1118
IUPAC/Chemical Name
methyl 4-(4-(piperidin-1-ylmethyl)benzamido)benzoate
InChi Key
ZYJBBZRSJADILJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H24N2O3/c1-26-21(25)18-9-11-19(12-10-18)22-20(24)17-7-5-16(6-8-17)15-23-13-3-2-4-14-23/h5-12H,2-4,13-15H2,1H3,(H,22,24)
SMILES Code
O=C(NC1=CC=C(C(OC)=O)C=C1)C2=CC=C(C=C2)CN3CCCCC3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
352.43
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
Discovery and Structural Optimization of 4-
(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola
and Marburg Virus Infections
Irina N. Gaisina*,†,‡, Norton P. Peet*,‡, Letitia Wong‡, Adam M. Schafer∥
, Han Cheng∥
, Manu
Anantpadma⊥,§, Robert A. Davey⊥,§, Gregory R. J. Thatcher†, Lijun Rong*,∥
†UICentre (Drug Discovery @ UIC) and Department of Pharmaceutical Sciences, College of
Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612,
United States
‡Chicago BioSolutions Inc., 2242 W Harrison Street, Chicago, Illinois 60612, United States
∥College of Medicine, Department of Microbiology and Immunology, University of Illinois at
Chicago, 909 S Wolcott Ave, Chicago, Illinois 60612, United States
⊥Texas Biomedical Research Institute, 8715 W Military Drive, San Antonio, Texas 78227, United
States
§Department of Microbiology, Boston University, 620 Albany Street, Boston, Massachusetts
02118, United States
https://reporter.nih.gov/project-details/9997781
