MedKoo Cat#: 128231 | Name: iCARM1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CARM1-IN-6 (iCARM1) is an effective and selective inhibitor of CARM1 with an IC50 value of 12.3 μM.

Chemical Structure

iCARM1
iCARM1
CAS#1269199-96-3

Theoretical Analysis

MedKoo Cat#: 128231

Name: iCARM1

CAS#: 1269199-96-3

Chemical Formula: C23H29N5O

Exact Mass: 391.2372

Molecular Weight: 391.52

Elemental Analysis: C, 70.56; H, 7.47; N, 17.89; O, 4.09

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
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Related CAS #
No Data
Synonym
iCARM1; CARM1-IN-6; CARM1-IN 6; CARM1 IN-6
IUPAC/Chemical Name
2-(4-(5-(furan-3-yl)-4-(p-tolyl)pyrimidin-2-yl)piperazin-1-yl)-N,N-dimethylethan-1-amine
InChi Key
VMPLYSNCOLJRCV-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H29N5O/c1-18-4-6-19(7-5-18)22-21(20-8-15-29-17-20)16-24-23(25-22)28-13-11-27(12-14-28)10-9-26(2)3/h4-8,15-17H,9-14H2,1-3H3
SMILES Code
CN(C)CCN(CC1)CCN1C2=NC=C(C(C3=CC=C(C)C=C3)=N2)C4=COC=C4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 391.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Peng BL, Ran T, Chen X, Ding JC, Wang ZR, Li WJ, Liu W. A CARM1 Inhibitor Potently Suppresses Breast Cancer Both In Vitro and In Vivo. J Med Chem. 2024 May 23;67(10):7921-7934. doi: 10.1021/acs.jmedchem.3c02315. Epub 2024 May 7. PMID: 38713486; PMCID: PMC11129188.