MedKoo Cat#: 145572 | Name: Glycylarginine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Glycylarginine is a synthetic substrate. Glycyl-Arginine has a greater cytotoxic effect compared to Lysyl-Aspartic acid.

Chemical Structure

Glycylarginine
Glycylarginine
CAS#18635-55-7

Theoretical Analysis

MedKoo Cat#: 145572

Name: Glycylarginine

CAS#: 18635-55-7

Chemical Formula: C8H17N5O3

Exact Mass: 231.1300

Molecular Weight: 231.26

Elemental Analysis: C, 41.55; H, 7.41; N, 30.28; O, 20.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Glycylarginine; NSC-334212;
IUPAC/Chemical Name
glycyl-L-arginine
InChi Key
JLXVRFDTDUGQEE-YFKPBYRVSA-N
InChi Code
1S/C8H17N5O3/c9-4-6(14)13-5(7(15)16)2-1-3-12-8(10)11/h5H,1-4,9H2,(H,13,14)(H,15,16)(H4,10,11,12)/t5-/m0/s1
SMILES Code
NCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 231.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Roche PC, Ryan RJ. Electrophoretic analysis of membrane proteases in the luteinized rat ovary. Endocrinology. 1986 Aug;119(2):495-501. doi: 10.1210/endo-119-2-495. PMID: 3525119. 2: Ishiura S, Anraku H, Kamo I, Koizumi H, Arahata K, Sugita H. Isolation of a Ca-dependent erythrolytic protein (perforin) from cytotoxic T-lymphocytes. J Biochem. 1987 Jul;102(1):9-12. doi: 10.1093/oxfordjournals.jbchem.a122045. PMID: 3499435. 3: Lacourse KA, Friis-Hansen L, Samuelson LC, Rehfeld JF. Altered processing of procholecystokinin in carboxypeptidase E-deficient fat mice: differential synthesis in neurons and endocrine cells. FEBS Lett. 1998 Sep 25;436(1):61-6. doi: 10.1016/s0014-5793(98)01099-0. PMID: 9771894. 4: Sevim Akan H, Şahal G, Karaca TD, Gürpınar ÖA, Maraş M, Doğan A. Evaluation of glycyl-arginine and lysyl-aspartic acid dipeptides for their antimicrobial, antibiofilm, and anticancer potentials. Arch Microbiol. 2023 Oct 31;205(12):365. doi: 10.1007/s00203-023-03724-4. PMID: 37906313. 5: Bleakman A, Smyth DG. Sequential processing reactions in the formation of hormone amides. Eur J Biochem. 1987 Aug 17;167(1):161-5. doi: 10.1111/j.1432-1033.1987.tb13318.x. PMID: 3113947. 6: Nikawa T, Towatari T, Katunuma N. Purification and characterization of cathepsin J from rat liver. Eur J Biochem. 1992 Feb 15;204(1):381-93. doi: 10.1111/j.1432-1033.1992.tb16647.x. PMID: 1740150. 7: Lacourse KA, Friis-Hansen L, Rehfeld JF, Samuelson LC. Disturbed progastrin processing in carboxypeptidase E-deficient fat mice. FEBS Lett. 1997 Oct 13;416(1):45-50. doi: 10.1016/s0014-5793(97)01164-2. PMID: 9369230.