hSMG-1 inhibitor 11j is an inhibitor of the PI3K-related kinase SMG1 (IC50 = 0.11 nM), a kinase involved in nonsense-mediated decay (NMD) of RNA.
MedKoo Cat#: 128078
Name: hSMG-1 Inhibitor 11j
CAS#: 1402452-15-6
Chemical Formula: C27H28ClN7O3S
Exact Mass: 565.1663
Molecular Weight: 566.08
Elemental Analysis: C, 57.29; H, 4.99; Cl, 6.26; N, 17.32; O, 8.48; S, 5.66
The following data is based on the product molecular weight 566.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
