Synonym
CPK20; CPK 20; CPK-20
IUPAC/Chemical Name
N-(1-(2,4-bis(trifluoromethyl)benzyl)indolin-5-yl)cyclohexanesulfonamide
InChi Key
LXIXLAOMFBGFKV-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H24F6N2O2S/c24-22(25,26)17-7-6-16(20(13-17)23(27,28)29)14-31-11-10-15-12-18(8-9-21(15)31)30-34(32,33)19-4-2-1-3-5-19/h6-9,12-13,19,30H,1-5,10-11,14H2
SMILES Code
O=S(C1CCCCC1)(NC2=CC3=C(N(CC4=CC=C(C(F)(F)F)C=C4C(F)(F)F)CC3)C=C2)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
506.51
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Gutermuth T, Lassig R, Portes MT, Maierhofer T, Romeis T, Borst JW, Hedrich
R, Feijó JA, Konrad KR. Pollen tube growth regulation by free anions depends on
the interaction between the anion channel SLAH3 and calcium-dependent protein
kinases CPK2 and CPK20. Plant Cell. 2013 Nov;25(11):4525-43. doi:
10.1105/tpc.113.118463. Epub 2013 Nov 26. PMID: 24280384; PMCID: PMC3875734.
2: Iraci N, Carotenuto L, Ciaglia T, Belperio G, Di Matteo F, Mosca I, Carleo G,
Giovanna Basilicata M, Ambrosino P, Turcio R, Puzo D, Pepe G, Gomez-Monterrey I,
Soldovieri MV, Di Sarno V, Campiglia P, Miceli F, Bertamino A, Ostacolo C,
Taglialatela M. In Silico Assisted Identification, Synthesis, and In
Vitro Pharmacological Characterization of Potent and Selective Blockers of
the Epilepsy-Associated KCNT1 Channel. J Med Chem. 2024 Jun 13;67(11):9124-9149.
doi: 10.1021/acs.jmedchem.4c00268. Epub 2024 May 23. PMID: 38782404; PMCID:
PMC11181338.
