BAY-2413555 is a selective positive allosteric modulator of the M2 Receptor (M2 PAM) to Restore Cardiac Autonomic Balance. BAY-2413555 exhibits an excellent in vitro and in vivo pharmacokinetic profile. BAY 2413555 showed very high selectivity in vitro and ex vivo and no agonistic or antagonistic effect on the M2 receptor. BAY-2413555 showed the best overall profile and was selected as a clinical candidate.
MedKoo Cat#: 128037
Name: BAY-2413555
CAS#: N/A
Chemical Formula: C23H17F9N4O4
Exact Mass: 584.1106
Molecular Weight: 584.40
Elemental Analysis: C, 47.27; H, 2.93; F, 29.26; N, 9.59; O, 10.95
The following data is based on the product molecular weight 584.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
