CPW-86-363 | CAS#84080-55-7 | cephalosporin

MedKoo Cat#: 145558 | Name: CPW-86-363

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CPW-86-363 is a novel carboxy-pyrazol-cephalosporin and CPW-86-363 is a new expanded-spectrum cephalosporin. CPW 86-363 is excreted into the bile.

Chemical Structure

CPW-86-363

CAS#84080-55-7

Theoretical Analysis

MedKoo Cat#: 145558

Name: CPW-86-363

CAS#: 84080-55-7

Chemical Formula: C17H17N9O7S2

Exact Mass: 523.0700

Molecular Weight: 523.50

Elemental Analysis: C, 39.00; H, 3.27; N, 24.08; O, 21.39; S, 12.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

CPW-86-363; CPW86363; CPW 86 363;

IUPAC/Chemical Name

(6R,7R)-7-((Z)-2-((carboxymethoxy)imino)-2-(1H-pyrazol-3-yl)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChi Key

AXCIEQAUBGQHIM-PCZSKDDWSA-N

InChi Code

1S/C17H17N9O7S2/c1-25-17(21-23-24-25)35-6-7-5-34-15-11(14(30)26(15)12(7)16(31)32)19-13(29)10(8-2-3-18-20-8)22-33-4-9(27)28/h2-3,11,15H,4-6H2,1H3,(H,18,20)(H,19,29)(H,27,28)(H,31,32)/b22-10-/t11-,15-/m1/s1

SMILES Code

[H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC(O)=O)\C4=NNC=C4)C(O)=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 523.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ganzinger U, Schatz F, Haberl H, Haslberger A, Schiel H, Hitzenberger G. Comparative pharmacokinetic analysis of latamoxef and CPW 86-363, a novel carboxy-pyrazol-cephalosporin and formation of N-methyl-thiotetrazole. Int J Clin Pharmacol Ther Toxicol. 1987 Mar;25(3):152-6. PMID: 3557743. 2: Ganzinger U, Haslberger A. Pharmacokinetics of cephalosporins in normal and septicemic rabbits. Antimicrob Agents Chemother. 1985 Oct;28(4):473-7. doi: 10.1128/AAC.28.4.473. PMID: 4073869; PMCID: PMC180286. 3: Haslberger AG, Ganzinger U, Reiter H, Schiel H, Millendorfer A. Alterations of pharmacokinetic properties of gentamicin, penicillin G and two cephalosporins in septicaemic rabbits. J Antimicrob Chemother. 1987 Aug;20(2):273-82. doi: 10.1093/jac/20.2.273. Erratum in: J Antimicrob Chemother 1988 May;21(5):691. PMID: 3667483. 4: Ganzinger U, Haslberger A, Schiel H, Omilian-Rosso R, Schütze E. Influence of endotoxin on the distribution of cephalosporins in rabbits. J Antimicrob Chemother. 1986 Jun;17(6):785-93. doi: 10.1093/jac/17.6.785. PMID: 3733592.