E17241 | CAS#1060968-92-4 | inducer of the expression of ABCA1 | ABCA1

MedKoo Cat#: 127977 | Name: E17241

Description:

WARNING: This product is for research use only, not for human or veterinary use.

E17241 is an inducer of the expression of ABCA1, the gene encoding ATP-binding cassette transporter 1; subfamily A (ABCA1).

Chemical Structure

E17241

CAS#1060968-92-4

Theoretical Analysis

MedKoo Cat#: 127977

Name: E17241

CAS#: 1060968-92-4

Chemical Formula: C15H14N2O2S2

Exact Mass: 318.0497

Molecular Weight: 318.41

Elemental Analysis: C, 56.58; H, 4.43; N, 8.80; O, 10.05; S, 20.14

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

E17241; E 17241; E-17241

IUPAC/Chemical Name

4-(1,3-dithiolan-2-yl)-N-(3-hydroxypyridin-2-yl)benzamide

InChi Key

IOZLWSWLSUBSJM-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H14N2O2S2/c18-12-2-1-7-16-13(12)17-14(19)10-3-5-11(6-4-10)15-20-8-9-21-15/h1-7,15,18H,8-9H2,(H,16,17,19)

SMILES Code

OC1=CC=CN=C1NC(C(C=C2)=CC=C2C3SCCS3)=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 318.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Sheng R, Li Y, Wu Y, Liu C, Wang W, Han X, Li Y, Lei L, Jiang X, Zhang Y, Zhang Y, Li S, Hong B, Liu C, Xu Y, Si S. A pan-PPAR agonist E17241 ameliorates hyperglycemia and diabetic dyslipidemia in KKAy mice via up-regulating ABCA1 in islet, liver, and white adipose tissue. Biomed Pharmacother. 2024 Mar;172:116220. doi: 10.1016/j.biopha.2024.116220. Epub 2024 Feb 2. PMID: 38308968.