MedKoo Cat#: 127949 | Name: Phylloflavan
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW 264.7 cells. Phylloflavan also inhibits the cytopathic effect of encephalomyocarditis virus on L929 fibroblast cells (38 U/mL).

Chemical Structure

Phylloflavan
Phylloflavan
CAS#98570-83-3

Theoretical Analysis

MedKoo Cat#: 127949

Name: Phylloflavan

CAS#: 98570-83-3

Chemical Formula: C26H26O10

Exact Mass: 498.1526

Molecular Weight: 498.48

Elemental Analysis: C, 62.65; H, 5.26; O, 32.10

Price and Availability

Size Price Availability Quantity
10mg USD 750.00 2 Weeks
25mg USD 1,250.00 2 Weeks
100mg USD 3,950.00 2 Weeks
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Related CAS #
No Data
Synonym
Phylloflavan; 9T7A4KA6YL; UNII-9T7A4KA6YL
IUPAC/Chemical Name
(2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl (S)-5-(3,4-dihydroxyphenyl)-3-hydroxypentanoate
InChi Key
FKDRTLFRRHQTGU-TYFWRAIDSA-N
InChi Code
InChI=1S/C26H26O10/c27-15(4-1-13-2-5-18(29)21(32)7-13)11-25(34)35-24-12-17-20(31)9-16(28)10-23(17)36-26(24)14-3-6-19(30)22(33)8-14/h2-3,5-10,15,24,26-33H,1,4,11-12H2/t15-,24-,26+/m0/s1
SMILES Code
O=C(C[C@@H](O)CCC1=CC(O)=C(O)C=C1)O[C@H]2CC3=C(O)C=C(O)C=C3O[C@@H]2C4=CC(O)=C(O)C=C4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 498.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Aloufi BH, Snoussi M, Sulieman AME. Antiviral Efficacy of Selected Natural Phytochemicals against SARS-CoV-2 Spike Glycoprotein Using Structure-Based Drug Designing. Molecules. 2022 Apr 8;27(8):2401. doi: 10.3390/molecules27082401. PMID: 35458599; PMCID: PMC9025634. 2: Kolodziej H, Kayser O, Kiderlen AF, Ito H, Hatano T, Yoshida T, Foo LY. Proanthocyanidins and related compounds: antileishmanial activity and modulatory effects on nitric oxide and tumor necrosis factor-alpha-release in the murine macrophage-like cell line RAW 264.7. Biol Pharm Bull. 2001 Sep;24(9):1016-21. doi: 10.1248/bpb.24.1016. PMID: 11558561.