MedKoo Cat#: 127922 | Name: ML303
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC90 = 155 nM), with an EC50 of 0.7 μM for Influenza A virus H1N1.

Chemical Structure

ML303
ML303
CAS#1638211-04-7

Theoretical Analysis

MedKoo Cat#: 127922

Name: ML303

CAS#: 1638211-04-7

Chemical Formula: C21H16F3N3O2

Exact Mass: 399.1195

Molecular Weight: 399.37

Elemental Analysis: C, 63.16; H, 4.04; F, 14.27; N, 10.52; O, 8.01

Price and Availability

Size Price Availability Quantity
25mg USD 350.00 2 Weeks
50mg USD 550.00 2 Weeks
100mg USD 950.00 2 Weeks
1g USD 4,250.00 2 Weeks
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Related CAS #
No Data
Synonym
ML303; ML 303; ML-303
IUPAC/Chemical Name
2-methoxy-4-(3-methyl-1-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenol
InChi Key
YBRHGNCGFMRGSV-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H16F3N3O2/c1-12-19-16(13-3-8-17(28)18(11-13)29-2)9-10-25-20(19)27(26-12)15-6-4-14(5-7-15)21(22,23)24/h3-11,28H,1-2H3
SMILES Code
OC1=CC=C(C2=CC=NC3=C2C(C)=NN3C4=CC=C(C(F)(F)F)C=C4)C=C1OC
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 399.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Patnaik S, Basu D, Dehdashti S, Zheng W, Ferrer M, Southall N, Taylor M, Engel DA, Marugan JJ. Discovery of Small Molecule Influenza Virus NS1 Antagonist. 2012 Apr 13 [updated 2013 Sep 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 24260784.