CJZ-3 is a lomerizine derivative. CJZ3 caused the accumulation of intracellular Rh123 in a time-dependent manner and significantly decreased the efflux of Rh123 from the cells. CJZ3 has a potent in vitro effect on the inhibition of P-gp function.
MedKoo Cat#: 145515
Name: CJZ-3
CAS#: 766508-73-0
Chemical Formula: C24H22Cl2F2N2
Exact Mass: 446.1100
Molecular Weight: 447.35
Elemental Analysis: C, 64.44; H, 4.96; Cl, 15.85; F, 8.49; N, 6.26
The following data is based on the product molecular weight 447.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
