MedKoo Cat#: 127639 | Name: NEU-1225

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NEU-1225 is a potent inhibitor of Trypanosoma brucei growth.

Chemical Structure

NEU-1225
NEU-1225
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 127639

Name: NEU-1225

CAS#: N/A

Chemical Formula: C12H13N5

Exact Mass: 227.1171

Molecular Weight: 227.27

Elemental Analysis: C, 63.42; H, 5.77; N, 30.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
NEU-1225; NEU1225; NEU 1225
IUPAC/Chemical Name
N-(4,5-dimethyl-1H-pyrazol-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-amine
InChi Key
SUFCXVOCIXGJIT-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H13N5/c1-7-8(2)16-17-11(7)15-10-4-6-14-12-9(10)3-5-13-12/h3-6H,1-2H3,(H3,13,14,15,16,17)
SMILES Code
CC1=C(C)NN=C1NC2=C(C=CN3)C3=NC=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 227.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
TY - JOUR T1 - Pharmacophore Identification and Structure–Activity Relationship Analysis of a Series of Substituted Azaindoles as Inhibitors of Trypanosoma brucei AU - Ferrins, Lori AU - Diaz, Rosario AU - Cordon-Obras, Carlos AU - Rojas-Barros, Domingo AU - Quotadamo, Antonio AU - Oehme, Daniel P. AU - Ceballos-Pérez, Gloria AU - Swaminathan, Uma AU - Pérez-Moreno, Guiomar AU - Bosch-Navarrete, Cristina AU - García-Hernández, Raquel AU - Gomez-Liñan, Claudia AU - Saura, Andreu AU - Ruiz-Perez, Luis Miguel AU - Gamarro, Francisco AU - Martinez-Martinez, Maria Santos AU - Manzano, Pilar AU - González-Pacanowska, Dolores AU - Navarro, Miguel AU - Pollastri, Michael P. Y1 - 2024/08/13 PY - 2024 DA - 2024/08/13 N1 - doi: 10.1021/acs.jmedchem.4c00785 DO - 10.1021/acs.jmedchem.4c00785 T2 - Journal of Medicinal Chemistry JF - Journal of Medicinal Chemistry JO - J. Med. Chem. PB - American Chemical Society SN - 0022-2623 M3 - doi: 10.1021/acs.jmedchem.4c00785 UR - https://doi.org/10.1021/acs.jmedchem.4c00785 ER -