Synonym
NEU-1225; NEU1225; NEU 1225
IUPAC/Chemical Name
N-(4,5-dimethyl-1H-pyrazol-3-yl)-1H-pyrrolo[2,3-b]pyridin-4-amine
InChi Key
SUFCXVOCIXGJIT-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H13N5/c1-7-8(2)16-17-11(7)15-10-4-6-14-12-9(10)3-5-13-12/h3-6H,1-2H3,(H3,13,14,15,16,17)
SMILES Code
CC1=C(C)NN=C1NC2=C(C=CN3)C3=NC=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
227.27
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
TY - JOUR
T1 - Pharmacophore Identification and Structure–Activity Relationship Analysis of a Series of Substituted Azaindoles as Inhibitors of Trypanosoma brucei
AU - Ferrins, Lori
AU - Diaz, Rosario
AU - Cordon-Obras, Carlos
AU - Rojas-Barros, Domingo
AU - Quotadamo, Antonio
AU - Oehme, Daniel P.
AU - Ceballos-Pérez, Gloria
AU - Swaminathan, Uma
AU - Pérez-Moreno, Guiomar
AU - Bosch-Navarrete, Cristina
AU - García-Hernández, Raquel
AU - Gomez-Liñan, Claudia
AU - Saura, Andreu
AU - Ruiz-Perez, Luis Miguel
AU - Gamarro, Francisco
AU - Martinez-Martinez, Maria Santos
AU - Manzano, Pilar
AU - González-Pacanowska, Dolores
AU - Navarro, Miguel
AU - Pollastri, Michael P.
Y1 - 2024/08/13
PY - 2024
DA - 2024/08/13
N1 - doi: 10.1021/acs.jmedchem.4c00785
DO - 10.1021/acs.jmedchem.4c00785
T2 - Journal of Medicinal Chemistry
JF - Journal of Medicinal Chemistry
JO - J. Med. Chem.
PB - American Chemical Society
SN - 0022-2623
M3 - doi: 10.1021/acs.jmedchem.4c00785
UR - https://doi.org/10.1021/acs.jmedchem.4c00785
ER -