PIM-35 is an indole derivative with effects in animals indicative of antidepressant properties. PIM-35 is a weak inhibitor of noradrenaline uptake as compared with the standards used. Chronic administration of PIM-35 produced no variation in the number or the affinity of alpha 2, beta 1- and beta 2-adrenoceptors. PIM-35 has activity on the serotonergic system and in this way is similar to the antidepressants paroxetine and chlorimipramine.
MedKoo Cat#: 145463
Name: PIM-35
CAS#: 130445-55-5
Chemical Formula: C10H12N2O
Exact Mass: 176.1000
Molecular Weight: 176.22
Elemental Analysis: C, 68.16; H, 6.86; N, 15.90; O, 9.08
The following data is based on the product molecular weight 176.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |