LR132 | CAS#135211-15-3 | sigma receptor ligand

MedKoo Cat#: 145433 | Name: LR132

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LR132 is a novel sigma receptor ligand with antagonist activity.

Chemical Structure

LR132

CAS#135211-15-3

Theoretical Analysis

MedKoo Cat#: 145433

Name: LR132

CAS#: 135211-15-3

Chemical Formula: C18H26Cl2N2

Exact Mass: 340.1500

Molecular Weight: 341.32

Elemental Analysis: C, 63.34; H, 7.68; Cl, 20.77; N, 8.21

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

LR132; LR 132;

IUPAC/Chemical Name

(1S,2R)-N-(3,4-dichlorophenethyl)-2-(pyrrolidin-1-yl)cyclohexan-1-amine

InChi Key

NREHOBGKKWFKES-ZWKOTPCHSA-N

InChi Code

1S/C18H26Cl2N2/c19-15-8-7-14(13-16(15)20)9-10-21-17-5-1-2-6-18(17)22-11-3-4-12-22/h7-8,13,17-18,21H,1-6,9-12H2/t17-,18+/m0/s1

SMILES Code

ClC1=C(Cl)C=C(CCN[C@H]2CCCC[C@H]2N3CCCC3)C=C1

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 341.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Matsumoto RR, McCracken KA, Friedman MJ, Pouw B, De Costa BR, Bowen WD. Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice. Eur J Pharmacol. 2001 May 11;419(2-3):163-74. doi: 10.1016/s0014-2999(01)00968-2. PMID: 11426838. 2: Carr DJ, De Costa BR, Radesca L, Blalock JE. Functional assessment and partial characterization of [3H](+)-pentazocine binding sites on cells of the immune system. J Neuroimmunol. 1991 Dec;35(1-3):153-66. doi: 10.1016/0165-5728(91)90170-c. PMID: 1955564.