MedKoo Cat#: 161186 | Name: VON40146
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

VON40146, also known as meso-Tetra(pentafluorophenyl)porphine chlorin free, is a synthetic porphyrin derivative. VON40146 is a catalyst for the generation of hydrogen gas in the presence of p-toluenesulfonic acid. VON40146 has applications in photodynamic therapy, as well as being able to generate products with nucleophiles at the para position of fluorine atoms. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming)

Chemical Structure

VON40146
VON40146
CAS#25440-14-6

Theoretical Analysis

MedKoo Cat#: 161186

Name: VON40146

CAS#: 25440-14-6

Chemical Formula: C44H10F20N4

Exact Mass: 974.0586

Molecular Weight: 974.56

Elemental Analysis: C, 54.23; H, 1.03; F, 38.99; N, 5.75

Price and Availability

Size Price Availability Quantity
100mg USD 445.00 2 Weeks
250mg USD 625.00 2 Weeks
500mg USD 870.00 2 Weeks
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Synonym
VON40146; VON40146; VON40146; meso-Tetra(pentafluorophenyl)porphine chlorin free; 5,10,15,20-tetrakis(perfluorophenyl)porphyrin;
IUPAC/Chemical Name
5,10,15,20-tetrakis(perfluorophenyl)porphyrin
InChi Key
VJEVAXUMNMFKDT-OTHQCIQNSA-N
InChi Code
InChI=1S/C44H10F20N4/c45-25-21(26(46)34(54)41(61)33(25)53)17-9-1-2-10(65-9)18(22-27(47)35(55)42(62)36(56)28(22)48)12-5-6-14(67-12)20(24-31(51)39(59)44(64)40(60)32(24)52)16-8-7-15(68-16)19(13-4-3-11(17)66-13)23-29(49)37(57)43(63)38(58)30(23)50/h1-8,65,68H/b17-9+,17-11+,18-10+,18-12+,19-13+,19-15+,20-14+,20-16+
SMILES Code
FC1=C(F)C(F)=C(F)C(/C2=C3N/C(C=C/3)=C(C4=C(F)C(F)=C(F)C(F)=C4F)\C5=N/C(C=C5)=C(C6=CC=C(/C(C7=C(F)C(F)=C(F)C(F)=C7F)=C8N=C2C=C\8)N6)/C9=C(F)C(F)=C(F)C(F)=C9F)=C1F
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 974.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1.) Samaroo, D., Vinodu, M., Chen, X., Drain, C. M., meso-Tetra(pentafluorophenyl)porphyrin as an Efficient Platform for Combinatorial Synthesis and the Selection of New Photodynamic Therapeutics using a Cancer Cell Line, Comb. Chem.2007, 9, 06, 998–1011. 2.) Samaroo, D., Soll, E. C., Todar, L.J., Drain, C. M., Efficient Microwave-Assisted Synthesis of Amine-Substituted Tetrakis(pentafluorophenyl)porphyrin, Org. Lett. 2006, 8, 22, 4985–4988. 3.) Wu, et al. Hydrogen gas generation using a metal-free fluorinated porphyrin Chem. Sci., 2018, 9, 4689-4695 DOI: 10.1039/C8SC00093J 4.) de Souza, et al. Porphyrins as Photoredox Catalysts in Csp2–H Arylations: Batch and Continuous Flow Approaches. J. Org. Chem. 2018, 83, 24, 15077–15086. 5.) Hemant Kumar, et al. Ultrafast Relaxation Dynamics of 5,10,15,20-meso-Tetrakis Pentafluorophenyl Porphyrin Studied by Fluorescence Up-Conversion and Transient Absorption Spectroscopy. J. Phys. Chem. A 2015, 119, 8, 1267–1278. 6.) Foletto, et al. A New Protocol for the Synthesis of New Thioaryl-Porphyrins Derived from 5,10,15,20-Tetrakis(pentafluorophenyl)porphyrin: Photophysical Evaluation and DNA-Binding Interactive Studies. Molecules 2018, 23(10), 2588; doi.org/10.3390/molecules23102588 7.) Wyrebek, et al. An Approach to Pyrazoline-Fused Chlorins by Dipolar [3 + 2]-Cycloaddition of Iminonitriles to meso-Tetrakis(pentafluorophenyl)porphyrin: Synthesis of New PDT Photosensitizers. Bulletin of the Chemical Society of Japan 2012, Vol.85, No.10 1167-1174https://doi.org/10.1246/bcsj.20110408