MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 150172 | Name: 2-Acetylpyridine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

2-Acetylpyridine is an aromatic ketone. 2-Acetylpyridine is found in Camellia sinensis, Mentha arvensis, and other organisms. As a flavoring agent, 2-Acetylpyridine contributes to the flavor of corn tortillas, popcorn, and beer.

Chemical Structure

2-Acetylpyridine
2-Acetylpyridine
CAS#1122-62-9

Theoretical Analysis

MedKoo Cat#: 150172

Name: 2-Acetylpyridine

CAS#: 1122-62-9

Chemical Formula: C7H7NO

Exact Mass: 121.0530

Molecular Weight: 121.14

Elemental Analysis: C, 69.41; H, 5.82; N, 11.56; O, 13.21

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
2-Acetylpyridine; 1-(pyridin-2-yl)ethanone; 1-pyridin-2-ylethanone; Methyl 2-pyridyl ketone;
IUPAC/Chemical Name
1-pyridin-2-ylethanone
InChi Key
AJKVQEKCUACUMD-UHFFFAOYSA-N
InChi Code
1S/C7H7NO/c1-6(9)7-4-2-3-5-8-7/h2-5H,1H3
SMILES Code
CC(C1=NC=CC=C1)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 121.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Oliveira APA, Ferreira IP, Despaigne AAR, Silva JGD, Vieira ACS, Santos MS, Alexandre-Moreira MS, Diniz R, Beraldo H. Structural studies and antileishmanial activity of 2-acetylpyridine and 2-benzoylpyridine nitroimidazole-derived hydrazones. Acta Crystallogr C Struct Chem. 2019 Mar 1;75(Pt 3):320-328. doi: 10.1107/S2053229619001529. Epub 2019 Feb 15. PMID: 30833527. 2: Lira AB, Parrilha GL, Dias GT, de Sousa Saraiva FS, Veríssimo GC, de Sousa RS, da Silva TG, de Oliveira Filho AA, Alves AF, de Souza-Fagundes EM, Beraldo H, Gomes MA, Diniz MFFM. Evaluation of Toxicity and Oxidative Stress of 2-Acetylpyridine-N(4)-orthochlorophenyl Thiosemicarbazone. Oxid Med Cell Longev. 2022 Mar 19;2022:4101095. doi: 10.1155/2022/4101095. PMID: 35345833; PMCID: PMC8957429. 3: Pal S, Pal S. trans-(2-Acetylpyridine-kappa2N,O)dichlorobis(dimethyl sulfoxide-kappaS)ruthenium(II). Acta Crystallogr C. 2002 May;58(Pt 5):m273-4. doi: 10.1107/s0108270102003797. Epub 2002 Apr 11. PMID: 11983963. 4: Oliveira AA, Perdigão GM, Rodrigues LE, da Silva JG, Souza-Fagundes EM, Takahashi JA, Rocha WR, Beraldo H. Cytotoxic and antimicrobial effects of indium(iii) complexes with 2-acetylpyridine-derived thiosemicarbazones. Dalton Trans. 2017 Jan 17;46(3):918-932. doi: 10.1039/c6dt03657k. PMID: 28009892. 5: Kitos AA, Efthymiou CG, Manos MJ, Tasiopoulos AJ, Nastopoulos V, Escuer A, Perlepes SP. Interesting copper(ii)-assisted transformations of 2-acetylpyridine and 2-benzoylpyridine. Dalton Trans. 2016 Jan 21;45(3):1063-77. doi: 10.1039/c5dt03912f. PMID: 26659333. 6: Despaigne AA, Parrilha GL, Izidoro JB, da Costa PR, dos Santos RG, Piro OE, Castellano EE, Rocha WR, Beraldo H. 2-Acetylpyridine- and 2-benzoylpyridine- derived hydrazones and their gallium(III) complexes are highly cytotoxic to glioma cells. Eur J Med Chem. 2012 Apr;50:163-72. doi: 10.1016/j.ejmech.2012.01.051. Epub 2012 Feb 2. PMID: 22357115. 7: Klayman DL, Scovill JP, Mason CJ, Bartosevich JF, Bruce J, Lin AJ. 2-Acetylpyridine thiosemicarbazones. 6.2-Acetylpyridine and 2-butyrylpyridine thiosemicarbazones as antileukemic agents. Arzneimittelforschung. 1983;33(7):909-12. doi: 10.1002/chin.198344210. PMID: 6684928. 8: Klaymann DL, Scovill JP, Bartosevich JF, Mason CJ. 2-Acetylpyridine thiosemicarbazones. 2. N4,N4-Disubstituted derivatives as potential antimalarial agents. J Med Chem. 1979 Nov;22(11):1367-73. doi: 10.1021/jm00197a017. PMID: 392099. 9: Easmon J, Puerstinger G, Roth T, Fiebig HH, Jenny M, Jaeger W, Heinisch G, Hofmann J. 2-benzoxazolyl and 2-benzimidazolyl hydrazones derived from 2-acetylpyridine: a novel class of antitumor agents. Int J Cancer. 2001 Oct 1;94(1):89-96. doi: 10.1002/ijc.1427. PMID: 11668483. 10: Klayman DL, Scovill JP, Bartosevich JF, Bruce J. 2-Acetylpyridine thiosemicarbazones. 5. 1-[1-(2-Pyridyl)ethyl]-3-thiosemicarbazides as potential antimalarial agents. J Med Chem. 1983 Jan;26(1):35-9. doi: 10.1021/jm00355a008. PMID: 6338234. 11: Richardson DR, Kalinowski DS, Richardson V, Sharpe PC, Lovejoy DB, Islam M, Bernhardt PV. 2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: redox activity, iron complexation and characterization of their antitumor activity. J Med Chem. 2009 Mar 12;52(5):1459-70. doi: 10.1021/jm801585u. PMID: 19216562. 12: Scovill JP, Klayman DL, Lambros C, Childs GE, Notsch JD. 2-Acetylpyridine thiosemicarbazones. 9. Derivatives of 2-acetylpyridine 1-oxide as potential antimalarial agents. J Med Chem. 1984 Jan;27(1):87-91. doi: 10.1021/jm00367a019. PMID: 6361258. 13: Klayman DL, Mason CJ, Scovill JP. 2-Acetylpyridine thiosemicarbazones. 10. 2-Propionyl-, 2-butyryl-, and 2-(2-methylpropionyl)pyridine thiosemicarbazones as potential antimalarial agents. Arzneimittelforschung. 1984;34(12):1701-3. PMID: 6397197. 14: Scovill JP, Klayman DL, Franchino CF. 2-Acetylpyridine thiosemicarbazones. 4. Complexes with transition metals as antimalarial and antileukemic agents. J Med Chem. 1982 Oct;25(10):1261-4. doi: 10.1021/jm00352a036. PMID: 6754934. 15: Stacy AE, Palanimuthu D, Bernhardt PV, Kalinowski DS, Jansson PJ, Richardson DR. Structure-Activity Relationships of Di-2-pyridylketone, 2-Benzoylpyridine, and 2-Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance. J Med Chem. 2016 Sep 22;59(18):8601-20. doi: 10.1021/acs.jmedchem.6b01050. Epub 2016 Aug 30. PMID: 27524608. 16: Lessa JA, Mendes IC, da Silva PR, Soares MA, dos Santos RG, Speziali NL, Romeiro NC, Barreiro EJ, Beraldo H. 2-Acetylpyridine thiosemicarbazones: cytotoxic activity in nanomolar doses against malignant gliomas. Eur J Med Chem. 2010 Dec;45(12):5671-7. doi: 10.1016/j.ejmech.2010.09.021. Epub 2010 Sep 17. PMID: 20884094.

View History

Endothal-Diammonium

Endothal-Diammonium