MedKoo Cat#: 150163 | Name: Glucametacin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Glucametacin is a non-steroidal anti-inflammatory, analgesic, antipyretic agent. Glucametacin is compared with ketoprofen in a double-blind, crossover trial.

Chemical Structure

Glucametacin
Glucametacin
CAS#52443-21-7

Theoretical Analysis

MedKoo Cat#: 150163

Name: Glucametacin

CAS#: 52443-21-7

Chemical Formula: C25H27ClN2O8

Exact Mass: 518.1460

Molecular Weight: 518.95

Elemental Analysis: C, 57.86; H, 5.24; Cl, 6.83; N, 5.40; O, 24.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Glucametacin; Glucametacine; Glucametacin [INN]; Teoremac;
IUPAC/Chemical Name
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide
InChi Key
XLVXAUNDHWERBM-IVGWJTKZSA-N
InChi Code
1S/C25H27ClN2O8/c1-13-17(10-22(32)27-19(11-29)23(33)24(34)21(31)12-30)18-9-16(36-2)7-8-20(18)28(13)25(35)14-3-5-15(26)6-4-14/h3-9,11,19,21,23-24,30-31,33-34H,10,12H2,1-2H3,(H,27,32)/t19-,21+,23+,24+/m0/s1
SMILES Code
O=C(N[C@H]([C@@H](O)[C@H](O)[C@H](O)CO)C=O)CC1=C(C)N(C(C2=CC=C(Cl)C=C2)=O)C3=C1C=C(OC)C=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 518.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Capelli L, Chianese V, La Montagna G, Giordano M. Further studies on glucametacin in rheumatoid arthritis and in other chronic types of rheumatism. Curr Med Res Opin. 1981;7(4):227-33. doi: 10.1185/03007998109114267. PMID: 6971729. 2: Ibba G, Uras R, Perpignano G. Double-blind comparison of glucametacin and ketoprofen in chronic arthropathies. Curr Med Res Opin. 1983;8(5):321-6. doi: 10.1185/03007998309112391. PMID: 6340973. 3: Akatsu T, Catanzaro Guimarães SA. Comparative effects of non-steroidal anti- inflammatory drugs, mefenamic acid, metiazinic acid and glucametacin on the inflammatory response induced by subcutaneous implantation of human dental plaque and on the mitotic activity of isoproterenol-stimulated parotid glands of rats. Cell Mol Biol. 1986;32(5):619-26. PMID: 3779763.