MedKoo Cat#: 161067 | Name: Pt(II) Coproporphyrin I
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pt(II) Coproporphyrin I is a porphyrin derivative which is a useful component in detecting intracellular O2. Pt(II) Coproporphyrin I conjugates are used as a homogeneous assay for cellular proteases.

Chemical Structure

Pt(II) Coproporphyrin I
Pt(II) Coproporphyrin I
CAS#90540-79-7

Theoretical Analysis

MedKoo Cat#: 161067

Name: Pt(II) Coproporphyrin I

CAS#: 90540-79-7

Chemical Formula: C36H36N4O8Pt

Exact Mass: 847.2181

Molecular Weight: 847.79

Elemental Analysis: C, 51.00; H, 4.28; N, 6.61; O, 15.10; Pt, 23.01

Price and Availability

Size Price Availability Quantity
1mg USD 720.00 2 Weeks
25mg USD 1,250.00 2 Weeks
50mg USD 1,900.00 2 Weeks
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Synonym
Pt(II) Coproporphyrin I; Pt (II) Coproporphyrin I; Pt(II) Coproporphyrin-I; Pt (II) Coproporphyrin-I; Pt(II) Coproporphyrin 1;
IUPAC/Chemical Name
n/a
InChi Key
ILNBPYGBDDICSC-MXOXSBADSA-L
InChi Code
InChI=1S/C36H38N4O8.Pt/c1-17-21(5-9-33(41)42)29-14-26-19(3)23(7-11-35(45)46)31(39-26)16-28-20(4)24(8-12-36(47)48)32(40-28)15-27-18(2)22(6-10-34(43)44)30(38-27)13-25(17)37-29;/h13-16H,5-12H2,1-4H3,(H6,37,38,39,40,41,42,43,44,45,46,47,48);/q;+2/p-2/b25-13-,26-14-,27-15-,28-16-,29-14-,30-13-,31-16-,32-15-;
SMILES Code
CC1=C(CCC(O)=O)C2=N/C1=C\C3=C(CCC(O)=O)C(C)=C4/C=C(C(CCC(O)=O)=C5C)\N=C5/C=C(N/6[Pt]N43)/C(CCC(O)=O)=C(C)C6=C\2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 847.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1.) Dmitriev. et al. Cell-Penetrating Conjugates of Coproporphyrins with Oligoarginine Peptides: Rational Design and Application for Sensing Intracellular O2. Bioconjugate Chem. 2011, 22, 12, 2507–2518. https://doi.org/10.1021/bc200324q 2.) Soini, et al. Preparation of monofunctional and phosphorescent palladium(II) and platinum(II) coproporphyrin labeling reagents. Journal of Porphyrins and Phthalocyanines. Vol. 05, No. 10, pp. 735-741 (2001). 3.) O’Riordan, et al. Homogeneous assays for cellular proteases employing the platinum(II)–coproporphyrin label and time-resolved phosphorescence. Analytical Biochemistry. Volume 342, Issue 1, 1 July 2005, Pages 111-119. https://doi.org/10.1016/j.ab.2005.04.016 4.) Soini, et al. Phosphorescent metalloporphyrins as labels in time-resolved luminescence microscopy: Effect of mounting on emission intensity. Microscopy Research & Technique. Volume 58, Issue 2 Special Issue: The Innervation of Bone 15 July 2002 Pages 125-131. https://doi.org/10.1002/jemt.10129 5.) Papkovsky, D.B., O’Riordan, T.C. Emerging Applications of Phosphorescent Metalloporphyrins. J Fluoresc 15, 569–584 (2005). https://doi.org/10.1007/s10895-005-2830-x