Synonym
Protoporphyrin IX disodium salt; Protoporphyrin-IX disodium salt; Protoporphyrin IX (2Na); Protoporphyrin IX disodium salt * 2Na;
IUPAC/Chemical Name
21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, sodium salt (1:2)
InChi Key
VWIKDHUBYGYUKW-HXFTUNQESA-L
InChi Code
InChI=1S/C34H34N4O4.2Na/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16,35,38H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42);;/q;2*+1/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;
SMILES Code
O=C(O[Na])CCC1=C2/C=C3C(CCC(O[Na])=O)=C(C)C(/C=C(N/4)/C(C)=C(C=C)C4=C\C5=N/C(C(C=C)=C5C)=C\C(N2)=C1C)=N/3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
606.63
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1.) Winslow S. Caughey, James A. Ibers, Crystal and Molecular Structure of the Free Base Porphyrin, Protoporphyrin IX Dimethyl Ester, J. Am. Chem. Soc. 99: 1977, 6639–6645.
2.) Battersby; C. J. R. Fookes; G. W. J. Matcham; E. McDonald, Biosynthesis of the pigments of life: formation of the macrocycle, Nature. 285: 1980, 17–21.
3.) Vedadi, Masoud; Niesen, Frank H.; Allali-Hassani, Abdellah; Fedorov, Oleg Y.; Finerty, Patrick J., Jr.; Wasney, Gregory A.; Yeung, Ron; Arrowsmith, Cheryl; Ball, Linda J.; Berglund, Helena; et al, Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination, Proceedings of the National Academy of Sciences of the United States of America (2006), 103(43), 15835-15840.
4.) Shi, Dong-Fang; Wheelhouse, Richard T.; Sun, Daekyu; Hurley, Laurence H., Quadruplex-Interactive Agents as Telomerase Inhibitors: Synthesis of Porphyrins and Structure-Activity Relationship for the Inhibition of Telomerase, Journal of Medicinal Chemistry (2001), 44(26), 4509-4523.
Protoporphyrin IX disodium salt CAS: 50865-01-5 MDL: MFCD00151108
