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MedKoo Cat#: 145374 | Name: DB-2073

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DB-2073 is an alkylresorcinol antibiotic. DB-2073 can be isolated in crystalline form from the fermented broth of Pseudomonas sp. B-9004.

Chemical Structure

DB-2073
DB-2073
CAS#39341-78-1

Theoretical Analysis

MedKoo Cat#: 145374

Name: DB-2073

CAS#: 39341-78-1

Chemical Formula: C15H24O2

Exact Mass: 236.1776

Molecular Weight: 236.36

Elemental Analysis: C, 76.23; H, 10.24; O, 13.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
DB-2073; DB2073; DB 2073;
IUPAC/Chemical Name
2-hexyl-5-propylbenzene-1,3-diol
InChi Key
VERGPVBZPMTZDY-UHFFFAOYSA-N
InChi Code
1S/C15H24O2/c1-3-5-6-7-9-13-14(16)10-12(8-4-2)11-15(13)17/h10-11,16-17H,3-9H2,1-2H3
SMILES Code
CCCCCCC1=C(O)C=C(CCC)C=C1O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 236.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kitahara T, Kanda N. DB-2073, a new alkylresorcinol antibiotic. II. The chemical structure of DB-2073. J Antibiot (Tokyo). 1975 Dec;28(12):943-6. doi: 10.7164/antibiotics.28.943. PMID: 1206007. 2: Kanda N, Ishizaki N, Inoue N, Oshima M, Handa A. DB-2073, a new alkylresorcinol antibiotic. I. Taxonomy, isolation and characterization. J Antibiot (Tokyo). 1975 Dec;28(12):935-42. doi: 10.7164/antibiotics.28.935. PMID: 1206006. 3: Schöner TA, Kresovic D, Bode HB. Biosynthesis and function of bacterial dialkylresorcinol compounds. Appl Microbiol Biotechnol. 2015 Oct;99(20):8323-8. doi: 10.1007/s00253-015-6905-6. Epub 2015 Aug 14. PMID: 26272097. 4: Pohanka A, Levenfors J, Broberg A. Antimicrobial dialkylresorcinols from Pseudomonas sp. Ki19. J Nat Prod. 2006 Apr;69(4):654-7. doi: 10.1021/np0600595. PMID: 16643045. 5: Thapa BB, Huo C, Budhathoki R, Chaudhary P, Joshi S, Poudel PB, Magar RT, Parajuli N, Kim KH, Sohng JK. Metabolic Comparison and Molecular Networking of Antimicrobials in Streptomyces Species. Int J Mol Sci. 2024 Apr 10;25(8):4193. doi: 10.3390/ijms25084193. PMID: 38673777; PMCID: PMC11050201. 6: Calderón CE, de Vicente A, Cazorla FM. Role of 2-hexyl, 5-propyl resorcinol production by Pseudomonas chlororaphis PCL1606 in the multitrophic interactions in the avocado rhizosphere during the biocontrol process. FEMS Microbiol Ecol. 2014 Jul;89(1):20-31. doi: 10.1111/1574-6941.12319. Epub 2014 Mar 31. PMID: 24641321. 7: Cazorla FM, Duckett SB, Bergström ET, Noreen S, Odijk R, Lugtenberg BJ, Thomas-Oates JE, Bloemberg GV. Biocontrol of avocado dematophora root rot by antagonistic Pseudomonas fluorescens PCL1606 correlates with the production of 2-hexyl 5-propyl resorcinol. Mol Plant Microbe Interact. 2006 Apr;19(4):418-28. doi: 10.1094/MPMI-19-0418. PMID: 16610745. 8: Kato S, Shindo K, Kawai H, Matsuoka M, Mochizuki J. Studies on free radical scavenging substances from microorganisms. III. Isolation and structural elucidation of a novel free radical scavenger, resorstatin. J Antibiot (Tokyo). 1993 Jun;46(6):1024-6. doi: 10.7164/antibiotics.46.1024. PMID: 8344864. 9: Calderón CE, Carrión VJ, de Vicente A, Cazorla FM. darR and darS are regulatory genes that modulate 2-hexyl, 5-propyl resorcinol transcription in Pseudomonas chlororaphis PCL1606. Microbiology (Reading). 2014 Dec;160(Pt 12):2670-2680. doi: 10.1099/mic.0.082677-0. Epub 2014 Sep 17. PMID: 25234473. 10: Itoh TJ, Schatten H, Schatten G, Mazia D, Kobayashi A, Sato H. T-1, a mitotic arrester, alters centrosome configurations in fertilized sea urchin eggs. Cell Motil Cytoskeleton. 1990;16(2):146-54. doi: 10.1002/cm.970160208. PMID: 2198112.