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MedKoo Cat#: 145371 | Name: Furanochromone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Furanochromone is a plant furyl compound.

Chemical Structure

Furanochromone
Furanochromone
CAS#67777-61-1

Theoretical Analysis

MedKoo Cat#: 145371

Name: Furanochromone

CAS#: 67777-61-1

Chemical Formula: C11H6O3

Exact Mass: 186.0317

Molecular Weight: 186.17

Elemental Analysis: C, 70.97; H, 3.25; O, 25.78

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Furanochromone;
IUPAC/Chemical Name
5H-furo[3,2-g]chromen-5-one
InChi Key
QBCCGEPNFFWJOU-UHFFFAOYSA-N
InChi Code
1S/C11H6O3/c12-9-2-4-14-11-6-10-7(1-3-13-10)5-8(9)11/h1-6H
SMILES Code
O=C1C=COC2=C1C=C3C=COC3=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 186.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PMID: 33874213. 9: Królicka A, Staniszewska I, Maliński E, Szafranek J, Lojkowska E. Stimulation of furanochromone accumulation in callus cultures of Ammi visnaga L. by addition of elicitors. Pharmazie. 2003 Aug;58(8):590-2. PMID: 12967041. 10: Jedrych Z, Borkowska G. Investigation of new benzofurane, benzopiran and furanochromone derivatives--potential antiarrhythmic and hypotensive agents. Pol J Pharmacol Pharm. 1983 Sep-Oct;35(5):397-403. PMID: 6664941. 11: Pereira J, Gonçalves R, Barreto M, Dias C, Carvalho F, Almeida AJ, Ribeiro HM, Marto J. Development of Gel-in-Oil Emulsions for Khellin Topical Delivery. Pharmaceutics. 2020 Apr 26;12(5):398. doi: 10.3390/pharmaceutics12050398. PMID: 32357441; PMCID: PMC7284555. 12: Harrison PG, Bailey BK, Steck W. Biosynthesis of furanochromones. Can J Biochem. 1971 Aug;49(8):964-70. doi: 10.1139/o71-140. PMID: 5120261. 13: Sansores-España D, Pech-Aguilar AG, Cua-Pech KG, Medina-Vera I, Guevara-Cruz M, Gutiérrez-Solis AL, Reyes-García JG, Avila-Nava A. Plants Used in Mexican Traditional Medicine for the Management of Urolithiasis: A Review of Preclinical Evidence, Bioactive Compounds, and Molecular Mechanisms. Molecules. 2022 Mar 21;27(6):2008. doi: 10.3390/molecules27062008. PMID: 35335370; PMCID: PMC8949565. 14: Fu HR, Li XS, Zhang YH, Feng BB, Pan LH. Visnagin ameliorates myocardial ischemia/reperfusion injury through the promotion of autophagy and the inhibition of apoptosis. Eur J Histochem. 2020 Sep 7;64(s2):3131. doi: 10.4081/ejh.2020.3131. PMID: 32909422; PMCID: PMC7482183. 15: Sharma R, Williams IS, Gatchie L, Sonawane VR, Chaudhuri B, Bharate SB. Khellinoflavanone, a Semisynthetic Derivative of Khellin, Overcomes Benzo[a]pyrene Toxicity in Human Normal and Cancer Cells That Express CYP1A1. ACS Omega. 2018 Aug 1;3(8):8553-8566. doi: 10.1021/acsomega.8b01088. PMID: 31458985; PMCID: PMC6645225. 16: Bharate SS. Enhancing Biopharmaceutical Attributes of Khellin by Amorphous Binary Solid Dispersions. AAPS PharmSciTech. 2021 Oct 27;22(8):260. doi: 10.1208/s12249-021-02126-3. PMID: 34705156. 17: Timotius KH, Rahayu I, Nurcahyanti ADR. Pimpinella pruatjan Molk: LC- MS/MS-QTFT Analysis of Bioactive Compounds from Decoction and Ethanol Extract of Aerial Parts. J Pharm Bioallied Sci. 2023 Jul-Sep;15(3):158-163. doi: 10.4103/jpbs.jpbs_183_22. Epub 2023 Aug 15. PMID: 37705859; PMCID: PMC10496851. 18: Rodrigues DF, Borges NHPB, Nogueira CES, Tavares JF, Arcanjo DDR, Barreto HM, Siqueira-Junior JP. Modulation of Drug Resistance by Furanochromones in NorA Overexpressing Staphylococcus Aureus. Evid Based Complement Alternat Med. 2022 Sep 17;2022:9244500. doi: 10.1155/2022/9244500. PMID: 36164399; PMCID: PMC9509268. 19: SEITZ G. Notiz über das 8-Methoxychellol (Ammiol), ein neues Furochromonderivat aus Ammi Visnaga L [Note on 8-methoxykhellol (ammiol), a new furanochromone derivative from Ammi visnaga L]. Arch Pharm Ber Dtsch Pharm Ges. 1954;287(2):79-82. Undetermined Language. doi: 10.1002/ardp.19542870209. PMID: 13149177. 20: Alsrhani A, Elderdery AY, Alzahrani B, Alzerwi NAN, Althobiti MM, Rayzah M, Idrees B, Elkhalifa AME, Subbiah SK, Mok PL. Therapeutic Potential of Albumin Nanoparticles Encapsulated Visnagin in MDA-MB-468 Triple-Negative Breast Cancer Cells. Molecules. 2023 Apr 4;28(7):3228. doi: 10.3390/molecules28073228. PMID: 37049991; PMCID: PMC10096807.