MedKoo Cat#: 161019 | Name: Cr(III) Mesoporphyrin IX chloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cr(III) Mesoporphyrin IX chloride is a porphyrin derivative. Mesoporphyrin IX chloride is a heme oxygenate inhibitor HO-1.

Chemical Structure

Cr(III) Mesoporphyrin IX chloride
Cr(III) Mesoporphyrin IX chloride
CAS#70948-71-9

Theoretical Analysis

MedKoo Cat#: 161019

Name: Cr(III) Mesoporphyrin IX chloride

CAS#: 70948-71-9

Chemical Formula: C34H36ClCrN4O4

Exact Mass: 651.1800

Molecular Weight: 652.13

Elemental Analysis: C, 62.62; H, 5.56; Cl, 5.44; Cr, 7.97; N, 8.59; O, 9.81

Price and Availability

Size Price Availability Quantity
25mg USD 632.00 2 Weeks
100mg USD 1,235.00 2 Weeks
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Synonym
Cr(III) Mesoporphyrin IX chloride; Cr (III) Mesoporphyrin IX chloride; Cr(III) Mesoporphyrin-IX chloride;
IUPAC/Chemical Name
n/a
InChi Key
FIWFYHUJMMDKCG-HXFTUNQESA-K
InChi Code
InChI=1S/C34H38N4O4.ClH.Cr/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h13-16H,7-12H2,1-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;
SMILES Code
CC(C(/C=C1/C(C)=C/2CCC(O)=O)=N/3)=C(CC)C3=C\C4=C(C)C(CC)=C5N4[Cr](Cl)N1C2=C/C(C(CCC(O)=O)=C/6C)=NC6=C/5
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 652.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1.) Barrier, et al. Involvement of Heme Oxygenase-1 in particulate matter-induced impairment of NO-dependent relaxation in rat intralobar pulmonary arteries. Toxicology in Vitro.Volume 32, April 2016, Pages 205-211. https://doi.org/10.1016/j.tiv.2016.01.005 2.) Jin, et al. Beneficial effects of early (but not late) intervention of heme oxygenase-1 on bleomycin-induced pulmonary fibrosis in mice. Respiratory Physiology & Neurobiology. Volume 175, Issue 2, 15 February 2011, Pages 239-246. https://doi.org/10.1016/j.resp.2010.11.010 3.) Olszanecki, et al. The Role of Haem Oxygenase-1 in the Decrease of Endothelial Intercellular Adhesion Molecule-1 Expression by Curcumin. BCPT Volume 101, Issue 6, December 2007 Pages 411-415. https://doi.org/10.1111/j.1742-7843.2007.00151.x 4.) Ding, et al. Downregulation of Carbon Monoxide as well as Nitric Oxide Contributes to Peripheral Chemoreflex Hypersensitivity in Heart Failure Rabbits. FASEB Journal. Volume 20, Issue 5, Experimental Biology 2006 (Part II) March 2006 Pages LB35-LB35. https://doi.org/10.1096/fasebj.20.5.LB35-a 5.) Browe, et al. Gaseotransmitters Modulate Inspiratory Drive from the Hypoglossal Nucleus. FASEB Journal. Volume 36, Issue S1, May 2022. https://doi.org/10.1096/fasebj.2022.36.S1.R4975 6.) Olszanecki, R., Kurnyta, M., Biedroń, R. et al. The role of heme oxygenase-1 in down regulation of PGE2 production by taurine chloramine and taurine bromamine in J774.2 macrophages. Amino Acids35, 359–364 (2008). https://doi.org/10.1007/s00726-007-0609-x