MedKoo Cat#: 150138 | Name: Tocophersolan

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tocophersolan is a polymeric, synthetic version of vitamin E. Due to its amphipathic property in which it forms its own micelles, tocophersolan is easily taken up into enterocytes, even in the absence of bile salts.

Chemical Structure

Tocophersolan
CAS#30999-06-5

Theoretical Analysis

MedKoo Cat#: 150138

Name: Tocophersolan

CAS#: 30999-06-5

Chemical Formula: C35H58O6

Exact Mass: 574.4230

Molecular Weight: 574.84

Elemental Analysis: C, 73.13; H, 10.17; O, 16.70

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Tocophersolan; Vitamin E TPGS; TPGS; Tocophersolan [USAN];
IUPAC/Chemical Name
1-O-(2-hydroxyethyl) 4-O-[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl] butanedioate
InChi Key
AOBORMOPSGHCAX-UHFFFAOYSA-N
InChi Code
1S/C35H58O6/c1-24(2)12-9-13-25(3)14-10-15-26(4)16-11-20-35(8)21-19-30-29(7)33(27(5)28(6)34(30)41-35)40-32(38)18-17-31(37)39-23-22-36/h24-26,36H,9-23H2,1-8H3
SMILES Code
O=C(OCCO)CCC(OC1=C(C)C(CCC(CCCC(C)CCCC(C)CCCC(C)C)(C)O2)=C2C(C)=C1C)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 574.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wande DP, Cui Q, Chen S, Xu C, Xiong H, Yao J. Rediscovering Tocophersolan: A Renaissance for Nano-Based Drug Delivery and Nanotheranostic Applications. Curr Drug Targets. 2021;22(8):856-869. doi: 10.2174/1389450121666200611140425. PMID: 32525772. 2: Bapat P, Ghadi R, Chaudhari D, Katiyar SS, Jain S. Tocophersolan stabilized lipid nanocapsules with high drug loading to improve the permeability and oral bioavailability of curcumin. Int J Pharm. 2019 Apr 5;560:219-227. doi: 10.1016/j.ijpharm.2019.02.013. Epub 2019 Feb 15. PMID: 30776407.