INS018-055 (ISM001-055, TNIK&MAP4K4-IN-2, compound 112) is an inhibitor of TNIK and MAP4K4. It exhibits an IC50 values of 12-120 nM on TNIK.
MedKoo Cat#: 127460
Name: INS018-055
CAS#: 2828567-39-9
Chemical Formula: C27H30FN7O
Exact Mass: 487.2496
Molecular Weight: 487.58
Elemental Analysis: C, 66.51; H, 6.20; F, 3.90; N, 20.11; O, 3.28
The following data is based on the product molecular weight 487.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
