IUPAC/Chemical Name
2-((6-amino-7H-purin-8-yl)amino)ethan-1-ol
InChi Key
CRWIVQWPUFWSCJ-UHFFFAOYSA-N
InChi Code
1S/C7H10N6O/c8-5-4-6(11-3-10-5)13-7(12-4)9-1-2-14/h3,14H,1-2H2,(H4,8,9,10,11,12,13)
SMILES Code
NC1=C2NC(NCCO)=NC2=NC=N1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
194.20
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Stepaniuk GI, Ornostaĭ VV, Kozlov VG. Sravnitel'naia otsenka ranozazhivliaiushchego deĭstviia benzofurokaina, étadena i ksantinola nikotinata v éksperimente [Comparative evaluation of the wound-healing effect of benzofuracaine, etaden, and xanthinol nicotinate in an experiment]. Patol Fiziol Eksp Ter. 1992 May-Jun;(3):16-8. Russian. PMID: 1480413.
2: Kuzina VA, Rusanov AM, Gavrilov RI. Vliianiw étadena na fermentativnuiu aktivnost' kishechnika u obluchennykh krys [Effect of etaden on intestinal enzymatic activity in irradiated rats]. Med Radiol (Mosk). 1978 May;23(3):69-71. Russian. PMID: 642738.
3: Korepanov AM, Murashov VS, Bazhenov EL. Dinamika nekotorykh pokazateleĭ belkovo-metabolicheskogo gomeostaza i sostoianie regeneratsii duodenal'noĭ slizistoĭ v protsesse lecheniia iazvnenoĭ bolezni dvenadtsatiperstnoĭ kishki étadenom [The dynamics of the indices of protein metabolic homeostasis and the status of duodenal mucosal regeneration during the etaden treatment of duodenal peptic ulcer]. Ter Arkh. 1992;64(2):52-5. Russian. PMID: 1509384.
4: Ornostaĭ VV, Stepaniuk GI. Vliianie benzofurokaina, étadena i ksantinola nikotinata na reparativnuiu regeneratsiiu kosteĭ v éksperimente [Effects of benzofurocaine, etaden and xanthinol nicotinate on reparative bone regeneration in animal experiments]. Ortop Travmatol Protez. 1991 Jul;(7):36-8. Russian. PMID: 1762734.
5: Kan Ch, Karimova RIa, Kravchenko LIa, Saidmuradova A. Lechenie trudnozazhivaiushchikh khronicheskikh iazv zheludka putem vvedeniia étadena v podslizistuiu obolochku organa [Treatment of non-healing chronic stomach ulcers by administration of etaden into the gastric submucosal layer]. Ter Arkh. 1988;60(1):83-6. Russian. PMID: 3363516.
6: Spivak AM, Reĭngardt BK, Korneĭchuk AV, Sorokina GK. Primenenie étadena u bol'nykh iazvennoĭ bolezh'iu [The use of etaden in patients with peptic ulcer]. Vrach Delo. 1988 Apr;(4):25-7. Russian. PMID: 3041676.
7: Gabelov AA, Nazyrova FA, Larionova LP, Rusanov AM, Novoselova GS. Lechenie mestnykh luchevykh povrezhdenii étadenom [Treatment of local radiation injuries with etaden]. Med Radiol (Mosk). 1977 Feb;22(2):52-6. Russian. PMID: 323630.
8: Rusanov AM, Novoselova GS, Smirnova GA. Lechenie étadenom éksperimental'noĭ luchevoĭ leĭkopenii [Treatment of experimental radiation leukopenia with Etaden]. Med Radiol (Mosk). 1967 Jul;12(7):79-80. Russian. PMID: 5603437.
9: Korepanov AM, Murashov VS, Martynov GN. Kompleksnaia kliniko- immunologicheskaia otsenka éffektivnosti étadena pri iazvennoĭ bolezni dvenadtsatiperstnoĭ kishki [Complex clinico-immunologic assessment of the efficacy of ethadene in treating duodenal ulcers]. Klin Med (Mosk). 1989 Jul;67(7):58-61. Russian. PMID: 2811217.
10: Kibrik BS, Krylova GO. Primenenie étadena v kompleksnom lechenii vpervye vyiavlennykh bol'nykh infil'trativnym tuberkulezom legkikh [The use of ethaden in the complex treatment of newly diagnosed patients with infiltrative tuberculosis of the lungs]. Probl Tuberk. 1990;(5):36-40. Russian. PMID: 2388891.
