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MedKoo Cat#: 145263 | Name: DRF-8417

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DRF-8417 is a novel oxazolidinone. DRF 8417 exhibits potent activity against Gram-positive pathogens with MIC(50) and MIC(90) values ranging from 0.06 to 1 mg/L.

Chemical Structure

DRF-8417
DRF-8417
CAS#439903-56-7

Theoretical Analysis

MedKoo Cat#: 145263

Name: DRF-8417

CAS#: 439903-56-7

Chemical Formula: C15H17N3O5S

Exact Mass: 351.0889

Molecular Weight: 351.38

Elemental Analysis: C, 51.27; H, 4.88; N, 11.96; O, 22.77; S, 9.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
DRF-8417; DRF8417; DRF 8417;
IUPAC/Chemical Name
O-methyl (S)-((2-oxo-3-(4-(2-oxooxazolidin-3-yl)phenyl)oxazolidin-5-yl)methyl)carbamothioate
InChi Key
VTVGNCICMNIBNG-LBPRGKRZSA-N
InChi Code
1S/C15H17N3O5S/c1-21-13(24)16-8-12-9-18(15(20)23-12)11-4-2-10(3-5-11)17-6-7-22-14(17)19/h2-5,12H,6-9H2,1H3,(H,16,24)/t12-/m0/s1
SMILES Code
COC(=S)NC[C@H]1CN(C(=O)O1)C2=CC=C(C=C2)N3CCOC3=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 351.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sreenivas K, Amarnath PV, Mallik A, Sarnaik H, Kumar NS, Takhi M, Trehan S, Kumar MS, Iqbal J, Rajagopalan R, Chakrabarti R. In vitro and in vivo antibacterial evaluation of DRF 8417, a new oxazolidinone. J Antimicrob Chemother. 2007 Jul;60(1):159-61. doi: 10.1093/jac/dkm116. Epub 2007 Apr 21. PMID: 17449889.