MedKoo Cat#: 127381 | Name: MR 24
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MR 24 is a potent and selective MST3 kinase binding inhibitor with >10 fold selectivity over MST4 (EC50 values from NanoBRET assay are 57 nM and 583 nM for MST3 and MST4 respectively).

Chemical Structure

MR 24
MR 24
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 127381

Name: MR 24

CAS#: N/A

Chemical Formula: C26H32Cl4N6O3

Exact Mass: 616.1290

Molecular Weight: 618.38

Elemental Analysis: C, 50.50; H, 5.22; Cl, 22.93; N, 13.59; O, 7.76

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
50mg USD 1,150.00 2 Weeks
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Related CAS #
No Data
Synonym
MR 24; MR24; MR-24
IUPAC/Chemical Name
8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride
InChi Key
GDJVKNSFYAPEKT-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H29ClN6O3.3ClH/c1-16-5-4-6-23(30-16)17-7-8-20(22(27)12-17)21-11-18-13-29-26(31-19(14-34)15-35)32-24(18)33(25(21)36)10-3-2-9-28;;;/h4-8,11-13,19,34-35H,2-3,9-10,14-15,28H2,1H3,(H,29,31,32);3*1H
SMILES Code
O=C1C(C2=CC=C(C3=NC(C)=CC=C3)C=C2Cl)=CC4=CN=C(NC(CO)CO)N=C4N1CCCCN.[H]Cl.[H]Cl.[H]Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 618.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL