2,3-Dihydroxybenzoic acid | CAS#303-38-8 | Phenol

MedKoo Cat#: 150063 | Name: 2,3-Dihydroxybenzoic acid

Description:

WARNING: This product is for research use only, not for human or veterinary use.

2,3-Dihydroxybenzoic acid is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta. 2,3-dihydroxybenzoic acid (DHB) has been safely administered to humans as an iron-chelating agent.

Chemical Structure

2,3-Dihydroxybenzoic acid

CAS#303-38-8

Theoretical Analysis

MedKoo Cat#: 150063

Name: 2,3-Dihydroxybenzoic acid

CAS#: 303-38-8

Chemical Formula: C7H6O4

Exact Mass: 154.0266

Molecular Weight: 154.12

Elemental Analysis: C, 54.55; H, 3.92; O, 41.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

2,3-Dihydroxybenzoic acid; Pyrocatechuic acid; o-Pyrocatechuic acid; 2-Pyrocatechuic acid;

IUPAC/Chemical Name

2,3-dihydroxybenzoic acid

InChi Key

GLDQAMYCGOIJDV-UHFFFAOYSA-N

InChi Code

1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11)

SMILES Code

O=C(O)C1=CC=CC(O)=C1O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 154.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: López-Goñi I, Moriyón I, Neilands JB. Identification of 2,3-dihydroxybenzoic acid as a Brucella abortus siderophore. Infect Immun. 1992 Nov;60(11):4496-503. doi: 10.1128/iai.60.11.4496-4503.1992. PMID: 1398964; PMCID: PMC258194. 2: Song M, Zhang X, Liu W, Feng J, Cui Y, Yao P, Wang M, Guo RT, Wu Q, Zhu D. 2,3-Dihydroxybenzoic Acid Decarboxylase from Fusarium oxysporum: Crystal Structures and Substrate Recognition Mechanism. Chembiochem. 2020 Oct 15;21(20):2950-2956. doi: 10.1002/cbic.202000244. Epub 2020 Jul 2. PMID: 32421914. 3: Hofer G, Sheng X, Braeuer S, Payer SE, Plasch K, Goessler W, Faber K, Keller W, Himo F, Glueck SM. Metal Ion Promiscuity and Structure of 2,3-Dihydroxybenzoic Acid Decarboxylase of Aspergillus oryzae. Chembiochem. 2021 Feb 15;22(4):652-656. doi: 10.1002/cbic.202000600. Epub 2020 Nov 23. PMID: 33090643; PMCID: PMC7894528. 4: Grootveld M, Halliwell B. 2,3-Dihydroxybenzoic acid is a product of human aspirin metabolism. Biochem Pharmacol. 1988 Jan 15;37(2):271-80. doi: 10.1016/0006-2952(88)90729-0. PMID: 3342084. 5: Sun X, Lin Y, Yuan Q, Yan Y. Biological production of muconic acid via a prokaryotic 2,3-dihydroxybenzoic acid decarboxylase. ChemSusChem. 2014 Sep;7(9):2478-81. doi: 10.1002/cssc.201402092. Epub 2014 Jul 17. PMID: 25045104.