MedKoo Cat#: 127373 | Name: PHI-101
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

PHI-101 is an orally active, potent third-generation inhibitor of FLT3 that overcomes resistance to multiple drug-resistant mutations.

Chemical Structure

PHI-101
PHI-101
CAS#2127107-15-5

Theoretical Analysis

MedKoo Cat#: 127373

Name: PHI-101

CAS#: 2127107-15-5

Chemical Formula: C19H19FN4O2S

Exact Mass: 386.1213

Molecular Weight: 386.45

Elemental Analysis: C, 59.05; H, 4.96; F, 4.92; N, 14.50; O, 8.28; S, 8.30

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
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Related CAS #
No Data
Synonym
PHI-101; PHI101; PHI 101; Lasmotinibum; Lasmotinib
IUPAC/Chemical Name
(S)-5-((3-fluorophenyl)ethynyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide
InChi Key
ULVAGWVTXBTFRN-AWEZNQCLSA-N
InChi Code
InChI=1S/C19H19FN4O2S/c20-13-4-1-3-12(9-13)6-7-15-10-16(24-19(21)26)17(27-15)18(25)23-14-5-2-8-22-11-14/h1,3-4,9-10,14,22H,2,5,8,11H2,(H,23,25)(H3,21,24,26)/t14-/m0/s1
SMILES Code
O=C(C1=C(NC(N)=O)C=C(C#CC2=CC=CC(F)=C2)S1)N[C@@H]3CNCCC3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 386.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL